Infect Chemother.  2015 Dec;47(4):278-302. 10.3947/ic.2015.47.4.278.

Middle East Respiratory Syndrome Infection Control and Prevention Guideline for Healthcare Facilities

Affiliations
  • 1Division of Infectious Diseases, Department of Internal Medicine, Incheon Medical Center, Incheon, Korea.
  • 2Division of Infectious Diseases, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine, Seoul, Korea. heejinmd@medimail.co.kr
  • 3Division of Infectious Diseases, Department of Internal Medicine, Anam Hospital, Korea University College of Medicine, Seoul, Korea.
  • 4Division of Infectious Diseases, Department of Internal Medicine, Seoul Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
  • 5Division of Infectious Diseases, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • 6Department of Infection Control, Korea University Guro Hospital, Seoul, Korea.
  • 7Department of Infection Control, Ewha Womens University Mokdong Hospital, Seoul, Korea.
  • 8Keonyang University College of Nursing, Daejeon, Korea.
  • 9Department of Infection Control, Konkuk University Seoul Hospital, Seoul, Korea.
  • 10Catholic University of Korea College of Nursing, Seoul, Korea.
  • 11Division of Infectious Diseases, Department of Internal Medicine, Seoul Metropolitan Government Seobuk Hospital, Seoul, Korea.
  • 12Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 13Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
  • 14Division of Infectious Diseases, Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea.
  • 15Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • 16Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea.
  • 17Division of Infectious Diseases, Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
  • 18Division of Infectious Diseases, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
  • 19Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • 20Division of Infectious Diseases, Department of Internal Medicine, Kangwon National University School of Medicine, Chucheon, Korea.
  • 21Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Middle East Respiratory Syndrome (MERS) is an acute viral respiratory illness with high mortality caused by a new strain of betacoronavirus (MERS-CoV). Since the report of the first patient in Saudi Arabia in 2012, large-scale outbreaks through hospital-acquired infection and inter-hospital transmission have been reported. Most of the patients reported in South Korea were also infected in hospital settings. Therefore, to eliminate the spread of MERS-CoV, infection prevention and control measures should be implemented with rigor. The present guideline has been drafted on the basis of the experiences of infection control in the South Korean hospitals involved in the recent MERS outbreak and on domestic and international infection prevention and control guidelines. To ensure efficient MERS-CoV infection prevention and control, care should be taken to provide comprehensive infection control measures including contact control, hand hygiene, personal protective equipment, disinfection, and environmental cleaning.

Keyword

Middle east respiratory syndrome coronavirus; Infection control; Personal protective equipment; Quarantine; Disinfection

MeSH Terms

Delivery of Health Care*
Disease Outbreaks
Disinfection
Hand Hygiene
Humans
Infection Control*
Korea
Middle East*
Mortality
Quarantine
Saudi Arabia

Figure

  • Figure 1 Control of close contacts of a laboratory-confirmed MERS-CoV infection case. MERS-CoV, middle east respiratory syndrome coronavirus; PCR, polymerase chain reaction; MERS, middle east respiratory syndrome.

  • Figure 2 A schematic of the procedures for donning/doffing of PPE depending on the physical space arrangement. PPE, personal protective equipment

  • Figure 3 Triple-packaging of diagnostic specimens (Category/Package: primary container, secondary container, outer package).

  • Figure 4 Movement of the autopsy team: taking off shoes and clothes and wearing a surgical gown and other PPE in the dress-in room (1), entering the autopsy room (2), taking off PPE and performing hand hygiene in the dress-out room (3), re-entering the dress-in room to put on the shoes and clothes (4) (adapted from WHO guideline [11]). PPE, personal protective equipment.


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