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Infect Chemother.  2012 Jun;44(3):197-200. 10.3947/ic.2012.44.3.197.

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Induced by Ethambutol and Rifampin

Affiliations
  • 1Department of Internal Medicine, Gachon University of Medicine and Science, Incheon, Korea. yspark@gilhospital.com
  • 2Department of Dermatology, Gachon University of Medicine and Science, Incheon, Korea.
  • 3Department of Laboratory Medicine, Gachon University of Medicine and Science, Incheon, Korea.

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a disorder which can be caused by treatment with a diverse collection of drugs, and it is characterized by fever, rash, lymphadenopathy, and internal organ involvement with eosinophilia. Although ethambutol and rifampin are popularly used to treat tuberculosis, there has been only one reported case of DRESS syndrome associated with ethambutol. DRESS syndrome associated with administration of rifampin have not been reported. In this report and discussion, we present the case of a patient suffering from DRESS syndrome induced by both ethambutol and rifampin.

Keyword

Ethambutol; Rifampin; DRESS syndrome

MeSH Terms

Eosinophilia
Ethambutol
Exanthema
Fever
Humans
Lymphatic Diseases
Rifampin
Stress, Psychological
Tuberculosis
Ethambutol
Rifampin
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