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Infect Chemother.  2010 Dec;42(6):415-419. 10.3947/ic.2010.42.6.415.

Successful Treatment of Recurrent Methicillin-resistant Staphylococcus aureus Bacteremia and Endocarditis by Linezolid, Valve Replacement, and Excisional Surgery of Limb in a Patient with Complicated Arteriovenous Malformation

Affiliations
  • 1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. paihj@hanyang.ac.kr
  • 2Department of Thoracic and Cardiovascular surgery, Hanyang University College of Medicine, Seoul, Korea.

Abstract

Vancomycin treatment failure in methicillin-resistant Staphylococcus aureus (MRSA) bacteremia patients has increased over the past decade. We experienced a case of repeated MRSA bacteremia resulting in left-side endocarditis in 38-year-old male with a huge complicated arteriovenous malformation in the left thigh. After vancomycin treatment failure, the patient was successfully treated with the administration of linezolid, leg amputation, and mitral valve replacement.

Keyword

Linezolid; Methicillin-Resistant Staphylococcus aureus; Endocarditis; Bacterial

MeSH Terms

Acetamides
Adult
Amputation
Arteriovenous Malformations
Bacteremia
Endocarditis
Extremities
Humans
Leg
Linezolid
Male
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus
Mitral Valve
Oxazolidinones
Thigh
Treatment Failure
Vancomycin
Acetamides
Oxazolidinones
Vancomycin
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