Infect Chemother.  2010 Feb;42(1):6-11. 10.3947/ic.2010.42.1.6.

General Features and Post-Exposure Prophylaxis of Rabies

• Park JS
• Han MG

• KMID: 2170273
• DOI: http://doi.org/10.3947/ic.2010.42.1.6

Abstract

Rabies is a representative zoonotic disease caused by rabies virus. The discriminative features of rabies are broad range of hosts including humans, a wide variety of incubation periods ranging from a few weeks to more than a year, ability to bring about acute fetal consequence, and scare pathological lesions. Although rabies is fatal, it is preventable disease by vaccination and post-exposure prophylaxis (PEP). This review will focus on general features of rabies, and immunoglobulin and vaccines for PEP.

Keyword

Rabies; vaccine; post-exposure prophylaxis

MeSH Terms

Humans
Immunoglobulins
Oligopeptides
Post-Exposure Prophylaxis
Rabies
Rabies virus
Vaccination
Vaccines
Immunoglobulins
Oligopeptides
Vaccines

Figure

• 

  Figure 1 High- and suspect-risk regions of rabies. High-risk and suspect-risk regions are indicated in blue and light blue, respectively. The areas where rabies in humans and animals was reported since 1993 were designated as high-risk region of rabies.

• 

  Figure 2 Guideline on post-exposure prophylaxis for animal bite patients (Korea CDC, 2007).

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  Figure 3 Management of animals to determine post-exposure treatment in 2008. (A) Bite cases by animals vaccinated to rabies. (B) Bite cases by unvaccinated animals.

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