Infect Chemother.  2009 Feb;41(1):58-61. 10.3947/ic.2009.41.1.58.

Two Cases of Bacteremia Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus

Affiliations
  • 1Department of Internal Medicine, Soonchunhyang University School of Medicine, Bucheon, Korea. mdchoo@schbc.ac.kr
  • 2Department of Laboratory Medicine, Soonchunhyang University School of Medicine, Bucheon, Korea.
  • 3Center for Antimicrobial Resistance and Microbial Genetics, University of Ulsan, Seoul, Korea.

Abstract

Recent reports have described an increasing incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in patients who do not exhibit established risk factors for healthcare exposure. We report two cases of CA-MRSA bacteremia complicated by vertebral osteomyelitis. Both of CA-MRSA isolates were resistant to beta-lactam agents, but susceptible to clindamycin, trimethoprim-sulfamethoxazole, gentamicin, ciprofloxacin, and tetracycline. Both isolates carried staphylococcal cassette chromosome mec (SCCmec) type IVA, and were identified as sequence type (ST) 72 by mlultilocus sequence typing (MLST). However, the Panton-Valentine leukocidin (PVL) gene was not identified.

Keyword

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA); Bacteremia

MeSH Terms

Bacteremia
Bacterial Toxins
Ciprofloxacin
Clindamycin
Delivery of Health Care
Exotoxins
Gentamicins
Humans
Incidence
Leukocidins
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus
Osteomyelitis
Risk Factors
Tetracycline
Trimethoprim, Sulfamethoxazole Drug Combination
Bacterial Toxins
Ciprofloxacin
Clindamycin
Exotoxins
Gentamicins
Leukocidins
Tetracycline

Cited by  1 articles

A Case of a Submandibular Abscess caused by Panton-Valentine leukocidin Positive USA 300 Community-associated Methicillin Resistant Staphylococcus aureus in a Foreign Resident of South Korea
Donghyong Jeong, Sangsoo Bae, Inyub Baek, Sangdong Kim, Boyean Kim, Ki Tae Kwon, Kwan Soo Ko, Shinwon Lee
Infect Chemother. 2012;44(6):495-498.    doi: 10.3947/ic.2012.44.6.495.


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