Infect Chemother.  2003 Oct;35(5):345-349.

Two Cases of Haemophilus parainfluenzae endocarditis

  • 1Department of Internal Medicine, Ewha Womans University Medical School, Seoul, Korea.
  • 2Department of Laboratory Medicine, Ewha Womans University Medical School, Seoul, Korea.


HACEK organisms are the normal flora of upper respiratory tract and orophaynx. They infect abnormal cardiac valves, causing subacute native valve endocarditis or prosthetic valve endocarditis more than one year after valve surgery. Haemophilus species are responsible for only 0.5-1% of all infectious endocarditis cases. Embolization occurs in 60% and the mortality rate ranges from 16-45% of cases of infective endocarditis caused by H. parainfluenzae. We report two cases of H. parainfluenzae endocarditis, one of them is a 25-year-old male with tricuspid valve vegetations complicated with pulmonary embolism and the other is a 22-year-old female presented with heart failure.


Haemophilus parainfluenzae; HACEK; Infective endocarditis
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