Clin Pediatr Hematol Oncol.
2015 Apr;22(1):76-79. 10.15264/cpho.2015.22.1.76.
A Case of Nasal Type Extranodal NK/T Cell Lymphoma Incidentally Detected in a Child
- Affiliations
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- 1Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea. swan93@lycos.co.kr
- 2Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea.
- 3Department of Pathology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea.
- KMID: 2168924
- DOI: http://doi.org/10.15264/cpho.2015.22.1.76
Abstract
- A nasal type extranodal NK/T-cell lymphoma (ENKL) is very rare in children. A pediatric nasal type ENKL is generally localized and is likely to have sensitivity to radiotherapy. The most common site is the upper airway tract, such as nasal region, Waldeyer's ring, paranasal sinuses and palates. It usually presents with nasal symptoms, such as obstruction or epistaxis. We describe our experience of concurrent chemoradiotherapy in a 13-year old boy having incidentally detected nasal type ENKL on laryngoscopic examination who did not have nasal symptoms. He received three cycles of dexamethasone (40 mg/day for 3 days), ifosfamide (1,000 mg/m2/day for 3 days), VP-16 (67 mg/m2/day for 3 days) and carboplatin (200 mg/m2 for 1 day) at 3-week intervals and 45 Gy intensity-modulated radiation therapy. He has been disease-free for 18 months after cessation of therapy.
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