Hanyang Med Rev.  2011 May;31(2):116-122. 10.7599/hmr.2011.31.2.116.

The Role of Transient Receptor Potential Channel in Pain

Affiliations
  • 1Department of Physiology, Hanyang University College of Medicine, Seoul, Korea. eurijj@naver.com

Abstract

Transient receptor potential (TRP) channels, a large family of receptor channel proteins, initially attracted researchers in the pain field as key molecules in nociception, but later they became known as more general transducer molecules for various physical stresses. In this review, I will discuss their roles in thermal and mechanical sensation, and then consider their contribution to physiological pain.

Keyword

Pain; Transient receptor potential channels; Thermo-sensor; Mechano-sensor; Transducer
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