Clin Exp Reprod Med.  2014 Mar;41(1):9-14. 10.5653/cerm.2014.41.1.9.

Comparison between intracytoplasmic sperm injection and intracytoplasmic morphologically selected sperm injection in oligo-astheno-teratozoospermia patients

Affiliations
  • 1Maria Fertility Hospital, Seoul, Korea. blue@mariababy.com
  • 2Fertility Research Center, Maria Medical Foundation, Seoul, Korea.

Abstract


OBJECTIVE
The aim of this study was to evaluate the efficiency of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with conventional ICSI and previous ICSI attempts in oligo-astheno-teratozoospermia (OAT) patients.
METHODS
The sperms were selected under high magnification (6,600x) and used to induce fertilization in previous ICSI patients by IMSI. These results were compared with previous conventional ICSI cycles in patients with OAT infertility.
RESULTS
These results demonstrated no significant difference in the fertilization rate between IMSI and previous ICSI cycles (67.7% vs. 65.0%). However, the pregnancy and implantation rates with IMSI were significantly higher than those of the ICSI cycles (33.3% vs. 12.5% and 14.6% vs. 5.4%, respectively; p<0.05). The miscarriage rate among pregnant patients (18.2% vs. 37.5%) showed no statistically significant difference between groups.
CONCLUSION
Compared to conventional ICSI, this study found that IMSI increased the IVF-ET success rates in patients with OAT.

Keyword

High magnification; Intracytoplasmic sperm injection; Intracytoplasmic morphologically selected sperm injection; Oligo-astheno-teratozoospermia

MeSH Terms

Abortion, Spontaneous
Avena
Female
Fertilization
Humans
Infertility
Pregnancy
Sperm Injections, Intracytoplasmic*
Spermatozoa*
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