Clin Endosc.  2016 Jan;49(1):26-29. 10.5946/ce.2016.49.1.26.

Challenges and Future of Wireless Capsule Endoscopy

• Saurin JC
• Beneche N
• Chambon C
• Pioche M

• KMID: 2166545
• DOI: http://doi.org/10.5946/ce.2016.49.1.26

Abstract

In 2015, capsule endoscopy was introduced as the main investigation method for small bowel mucosal diseases, and its role in colonic diseases has been gradually revealed. Future challenges for capsule endoscopy, besides improvements of image quality and visualization of each part of the small bowel and colonic mucosa, include the development of gastric capsules, the capacity to perform histological examination of the mucosa, and maybe in the future, some capsule endoscopy-driven therapeutics. The aim of this review was to evaluate the clinical demands and feasibility of achieving the aforementioned objectives.

Keyword

Capsule endoscopy; Small bowel; Colon; Stomach; Forecasting

MeSH Terms

Capsule Endoscopy*
Capsules
Colon
Colonic Diseases
Forecasting
Mucous Membrane
Stomach
Capsules

Reference

1. Saurin JC, Delvaux M, Gaudin JL, et al. Diagnostic value of endoscopic capsule in patients with obscure digestive bleeding: blinded comparison with video push-enteroscopy. Endoscopy. 2003; 35:576–584.

2. Saurin JC, Delvaux M, Vahedi K, et al. Clinical impact of capsule endoscopy compared to push enteroscopy: 1-year follow-up study. Endoscopy. 2005; 37:318–323.

3. Saurin JC, Lapalus MG, Cholet F, et al. Can we shorten the small-bowel capsule reading time with the “Quick-view” image detection system? Dig Liver Dis. 2012; 44:477–481.

4. Spada C, Hassan C, Munoz-Navas M, et al. Second-generation colon capsule endoscopy compared with colonoscopy. Gastrointest Endosc. 2011; 74:581–589. e1.

5. Van Gossum A, Munoz-Navas M, Fernandez-Urien I, et al. Capsule endoscopy versus colonoscopy for the detection of polyps and cancer. N Engl J Med. 2009; 361:264–270.

6. Subramanian V, Mannath J, Telakis E, Ragunath K, Hawkey CJ. Efficacy of new playback functions at reducing small-bowel wireless capsule endoscopy reading times. Dig Dis Sci. 2012; 57:1624–1628.

7. May A, Friesing-Sosnik T, Manner H, Pohl J, Ell C. Long-term outcome after argon plasma coagulation of small-bowel lesions using double-balloon enteroscopy in patients with mid-gastrointestinal bleeding. Endoscopy. 2011; 43:759–765.

8. Li X, Chen H, Dai J, Gao Y, Ge Z. Predictive role of capsule endoscopy on the insertion route of double-balloon enteroscopy. Endoscopy. 2009; 41:762–766.

9. Gay G, Delvaux M, Fassler I. Outcome of capsule endoscopy in determining indication and route for push-and-pull enteroscopy. Endoscopy. 2006; 38:49–58.

10. Karargyris A, Koulaouzidis A. Capsule-odometer: a concept to improve accurate lesion localisation. World J Gastroenterol. 2013; 19:5943–5946.

11. Gora MJ, Sauk JS, Carruth RW, et al. Tethered capsule endomicroscopy enables less invasive imaging of gastrointestinal tract microstructure. Nat Med. 2013; 19:238–240.

12. Sauk J, Coron E, Kava L, et al. Interobserver agreement for the detection of Barrett’s esophagus with optical frequency domain imaging. Dig Dis Sci. 2013; 58:2261–2265.

13. Valdastri P, Quaglia C, Susilo E, et al. Wireless therapeutic endoscopic capsule: in vivo experiment. Endoscopy. 2008; 40:979–982.

14. Bhardwaj A, Hollenbeak CS, Pooran N, Mathew A. A meta-analysis of the diagnostic accuracy of esophageal capsule endoscopy for Barrett’s esophagus in patients with gastroesophageal reflux disease. Am J Gastroenterol. 2009; 104:1533–1539.

15. Heresbach D, Leray E, d’Halluin PN, et al. Diagnostic accuracy of esophageal capsule endoscopy versus conventional upper digestive endoscopy for suspected esophageal squamous cell carcinoma. Endoscopy. 2010; 42:93–97.

16. Denzer UW, Rösch T, Hoytat B, et al. Magnetically guided capsule versus conventional gastroscopy for upper abdominal complaints: a prospective blinded study. J Clin Gastroenterol. 2015; 49:101–107.

17. Rahman I, Pioche M, Shim CS, et al. Magnet assisted capsule endoscopy (MACE) in the upper GI tract is feasible: first human series using the novel Mirocam-Navi system. Gastrointest Endosc. 2014; 79(5 Suppl):AB22.

18. Pioche M, Vanbiervliet G, Jacob P, et al. Prospective randomized comparison between axial- and lateral-viewing capsule endoscopy systems in patients with obscure digestive bleeding. Endoscopy. 2014; 46:479–484.