Cancer Res Treat.  2006 Jun;38(3):184-188.

Long-term Survival after Surgical Resection for Liver Metastasis from Gastric Cancer: Two Case Reports

• Lim JK
• Ahn JB
• Cheon SH
• Chang H
• Jung JY
• Rha SY
• Roh JK
• Noh SH
• Kim HG
• Chung HC
• Jeung HC

Abstract

Surgical resection of colorectal cancer metastasis to the liver results in a 5-year survival rate of around 40%. Liver metastasis from other cancers such as neuroendocrine carcinoma and genitourinary tumors are also treated effectively with combined liver resection. However, hepatic metastasectomy for liver tumor from gastric cancer hasn't been considered as a standard treatment, and the benefit for this treatment has not been established. We report here on two cases of gastrectomy and combined liver resection for synchronous liver metastasis without any evidence of other metastatic lesions, and these two patients have survived for more than 7 years without evidence of disease recurrence. In conclusion, for patients with hepatic metastasis from gastric cancer, combined surgical resection of the liver metastasis should be considered as a treatment option when metastasis to other sites can be excluded.

Keyword

Stomach neoplasms; Liver resection; Long-term survival

MeSH Terms

Carcinoma, Neuroendocrine
Colorectal Neoplasms
Gastrectomy
Humans
Liver*
Metastasectomy
Neoplasm Metastasis*
Recurrence
Stomach Neoplasms*
Survival Rate

Figure

• 

  Fig. 1 The macroscopic and microscopic finding of the first case. (A) and (B), gross findings of the gastrectomized stomach showing an ulcerofungating mass (arrow) that measured 3.5×4.0 cm on the posterior wall of the antrum. (C) Poorly differentiated adenocarcinoma with lymphocytic infiltrates in the surrounding stroma of the stomach (H&E, ×40). (D) Microscopic findings of the metastatic adenonocarcinoma of the liver (H&E, ×40).

• 

  Fig. 2 The macroscopic and microscopic findings of the second case. (A) Removed stomach and spleen with a 7×9 cm sized ulcerative lesion on the posterior wall of the cardia and upper body. (B) The resected segment 8 of the liver showing a well-circumscribed 4×4 cm sized, friable gray tan nodular area on the cut section. It grossly abuts to one of the surgical margins. (C) Moderately differentiated adenocarcinoma of stomach (H&E, ×40). (D) Metastatic adenocarcinoma of the liver (H&E, ×40).

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