Clin Endosc.  2013 Sep;46(5):506-514.

Pancreatic Fluid Collection Drainage by Endoscopic Ultrasound: An Update

Affiliations
  • 1Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY, USA.
  • 2Division of Gastroenterology and Hepatology, New York Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA. mkahaleh@gmail.com

Abstract

Endoscopic management of symptomatic pancreatic fluid collections (PFCs) is now considered to be first line therapy. Expanded use of endoscopic ultrasound (EUS) techniques has resulted in increased applicability, safety, and efficacy of endoscopic transluminal PFC drainage. Steps include EUS-guided trangastric or transduodenal fistula creation into the PFC followed by stent placement or nasocystic drain deployment in order to decompress the collection. With the remarkable improvement in the available accessories and stents and development of exchange free access device; EUS drainage techniques have become simpler and less time consuming. The use of self-expandable metal stents with modifications to drain PFC has helped in overcoming some previously encountered challenges. PFCs considered suitable for endoscopic drainage include collection present for greater than 4 weeks, possessing a well-formed wall, position accessible endoscopically and located within 1 cm of the duodenal or gastric walls. Indications for EUS-guided drainage have been increasing which include unusual location of the collection, small window of entry, nonbulging collections, coagulopathy, intervening varices, failed conventional transmural drainage, indeterminate adherence of PFC to the luminal wall or suspicion of malignancy. In this article, we present a review of literature to date and discuss the recent developments in EUS-guided PFC drainage.

Keyword

Endosonography; Pancreatic fluid collections; Pancreatic pseudocyst; Nonbulging pancreatic fluid collections

MeSH Terms

Drainage
Endosonography
Fistula
Pancreatic Pseudocyst
Phenobarbital
Stents
Varicose Veins
Phenobarbital

Figure

  • Fig. 1 Endoscopic ultrasound view of the needle puncture.

  • Fig. 2 Fluoroscopic view of guidewire placed through the stomach wall.

  • Fig. 3 Fluoroscopic view of guidewire within the pancreatic fluid collection.

  • Fig. 4 Fluoroscopic view of balloon dilation of the tract.

  • Fig. 5 Endoscopic view of balloon dilation of the tract.

  • Fig. 6 Endoscopic view of deployed metal stent.

  • Fig. 7 Fluoroscopic view of the pigtails placed within the metal stent.


Reference

1. Baron TH, Thaggard WG, Morgan DE, Stanley RJ. Endoscopic therapy for organized pancreatic necrosis. Gastroenterology. 1996; 111:755–764. PMID: 8780582.
Article
2. Baillie J. Pancreatic pseudocysts (Part I). Gastrointest Endosc. 2004; 59:873–879. PMID: 15173808.
Article
3. Yeo CJ, Cameron JL, Sohn TA, et al. Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg. 1997; 226:248–257. PMID: 9339931.
4. Arvanitakis M, Delhaye M, Chamlou R, et al. Endoscopic therapy for main pancreatic-duct rupture after Silastic-ring vertical gastroplasty. Gastrointest Endosc. 2005; 62:143–151. PMID: 15990839.
Article
5. Klöppel G. Pseudocysts and other non-neoplastic cysts of the pancreas. Semin Diagn Pathol. 2000; 17:7–15. PMID: 10721803.
6. Bradley EL 3rd. A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. Arch Surg. 1993; 128:586–590. PMID: 8489394.
7. Baron TH, Harewood GC, Morgan DE, Yates MR. Outcome differences after endoscopic drainage of pancreatic necrosis, acute pancreatic pseudocysts, and chronic pancreatic pseudocysts. Gastrointest Endosc. 2002; 56:7–17. PMID: 12085029.
Article
8. Baron TH, Morgan DE. The diagnosis and management of fluid collections associated with pancreatitis. Am J Med. 1997; 102:555–563. PMID: 9217671.
9. Yeo CJ, Bastidas JA, Lynch-Nyhan A, Fishman EK, Zinner MJ, Cameron JL. The natural history of pancreatic pseudocysts documented by computed tomography. Surg Gynecol Obstet. 1990; 170:411–417. PMID: 2326721.
10. Bradley EL, Clements JL Jr, Gonzalez AC. The natural history of pancreatic pseudocysts: a unified concept of management. Am J Surg. 1979; 137:135–141. PMID: 758840.
Article
11. Gouyon B, Lévy P, Ruszniewski P, et al. Predictive factors in the outcome of pseudocysts complicating alcoholic chronic pancreatitis. Gut. 1997; 41:821–825. PMID: 9462217.
Article
12. Warshaw AL, Rattner DW. Timing of surgical drainage for pancreatic pseudocyst. Clinical and chemical criteria. Ann Surg. 1985; 202:720–724. PMID: 4073984.
13. Bradley EL 3rd. A fifteen year experience with open drainage for infected pancreatic necrosis. Surg Gynecol Obstet. 1993; 177:215–222. PMID: 8356492.
14. Boerma D, van Gulik TM, Obertop H, Gouma DJ. Internal drainage of infected pancreatic pseudocysts: safe or sorry? Dig Surg. 1999; 16:501–505. PMID: 10805550.
Article
15. vanSonnenberg E, Wittich GR, Casola G, et al. Percutaneous drainage of infected and noninfected pancreatic pseudocysts: experience in 101 cases. Radiology. 1989; 170(3 Pt 1):757–761. PMID: 2644662.
Article
16. Ahearne PM, Baillie JM, Cotton PB, Baker ME, Meyers WC, Pappas TN. An endoscopic retrograde cholangiopancreatography (ERCP)-based algorithm for the management of pancreatic pseudocysts. Am J Surg. 1992; 163:111–115. PMID: 1733357.
Article
17. Adams DB, Harvey TS, Anderson MC. Percutaneous catheter drainage of infected pancreatic and peripancreatic fluid collections. Arch Surg. 1990; 125:1554–1557. PMID: 2244807.
Article
18. Neff R. Pancreatic pseudocysts and fluid collections: percutaneous approaches. Surg Clin North Am. 2001; 81:399–403. PMID: 11392426.
19. Binmoeller KF, Seifert H, Walter A, Soehendra N. Transpapillary and transmural drainage of pancreatic pseudocysts. Gastrointest Endosc. 1995; 42:219–224. PMID: 7498686.
Article
20. Cahen D, Rauws E, Fockens P, Weverling G, Huibregtse K, Bruno M. Endoscopic drainage of pancreatic pseudocysts: long-term outcome and procedural factors associated with safe and successful treatment. Endoscopy. 2005; 37:977–983. PMID: 16189770.
Article
21. Hookey LC, Debroux S, Delhaye M, Arvanitakis M, Le Moine O, Devière J. Endoscopic drainage of pancreatic-fluid collections in 116 patients: a comparison of etiologies, drainage techniques, and outcomes. Gastrointest Endosc. 2006; 63:635–643. PMID: 16564865.
Article
22. Delhaye M, Matos C, Devière J. Endoscopic management of chronic pancreatitis. Gastrointest Endosc Clin N Am. 2003; 13:717–742. PMID: 14986795.
Article
23. Giovannini M. EUS-guided pancreatic pseudocyst drainage. Tech Gastrointest Endosc. 2007; 9:32–38.
Article
24. Howell DA, Holbrook RF, Bosco JJ, Muggia RA, Biber BP. Endoscopic needle localization of pancreatic pseudocysts before transmural drainage. Gastrointest Endosc. 1993; 39:693–698. PMID: 8224695.
Article
25. Antillon MR, Shah RJ, Stiegmann G, Chen YK. Single-step EUS-guided transmural drainage of simple and complicated pancreatic pseudocysts. Gastrointest Endosc. 2006; 63:797–803. PMID: 16650541.
Article
26. Sanchez Cortes E, Maalak A, Le Moine O, et al. Endoscopic cystenterostomy of nonbulging pancreatic fluid collections. Gastrointest Endosc. 2002; 56:380–386. PMID: 12196776.
27. Arvanitakis M, Delhaye M, Bali MA, et al. Pancreatic-fluid collections: a randomized controlled trial regarding stent removal after endoscopic transmural drainage. Gastrointest Endosc. 2007; 65:609–619. PMID: 17324413.
Article
28. Baron TH. Endoscopic drainage of pancreatic pseudocysts. J Gastrointest Surg. 2008; 12:369–372. PMID: 17906903.
Article
29. Giovannini M, Pesenti C, Rolland AL, Moutardier V, Delpero JR. Endoscopic ultrasound-guided drainage of pancreatic pseudocysts or pancreatic abscesses using a therapeutic echo endoscope. Endoscopy. 2001; 33:473–477. PMID: 11437038.
Article
30. Azar RR, Oh YS, Janec EM, Early DS, Jonnalagadda SS, Edmundowicz SA. Wire-guided pancreatic pseudocyst drainage by using a modified needle knife and therapeutic echoendoscope. Gastrointest Endosc. 2006; 63:688–692. PMID: 16564874.
Article
31. Krüger M, Schneider AS, Manns MP, Meier PN. Endoscopic management of pancreatic pseudocysts or abscesses after an EUS-guided 1-step procedure for initial access. Gastrointest Endosc. 2006; 63:409–416. PMID: 16500388.
Article
32. Kahaleh M, Shami VM, Conaway MR, et al. Endoscopic ultrasound drainage of pancreatic pseudocyst: a prospective comparison with conventional endoscopic drainage. Endoscopy. 2006; 38:355–359. PMID: 16680634.
Article
33. Lopes CV, Pesenti C, Bories E, Caillol F, Giovannini M. Endoscopic-ultrasound-guided endoscopic transmural drainage of pancreatic pseudocysts and abscesses. Scand J Gastroenterol. 2007; 42:524–529. PMID: 17454865.
34. Varadarajulu S, Wilcox CM, Tamhane A, Eloubeidi MA, Blakely J, Canon CL. Role of EUS in drainage of peripancreatic fluid collections not amenable for endoscopic transmural drainage. Gastrointest Endosc. 2007; 66:1107–1119. PMID: 17892874.
Article
35. Barthet M, Lamblin G, Gasmi M, Vitton V, Desjeux A, Grimaud JC. Clinical usefulness of a treatment algorithm for pancreatic pseudocysts. Gastrointest Endosc. 2008; 67:245–252. PMID: 18226686.
Article
36. Varadarajulu S, Christein JD, Tamhane A, Drelichman ER, Wilcox CM. Prospective randomized trial comparing EUS and EGD for transmural drainage of pancreatic pseudocysts (with videos). Gastrointest Endosc. 2008; 68:1102–1111. PMID: 18640677.
Article
37. Bakker OJ, van Santvoort HC, van Brunschot S, et al. Endoscopic transgastric vs surgical necrosectomy for infected necrotizing pancreatitis: a randomized trial. JAMA. 2012; 307:1053–1061. PMID: 22416101.
Article
38. Seewald S, Ang TL, Richter H, et al. Long-term results after endoscopic drainage and necrosectomy of symptomatic pancreatic fluid collections. Dig Endosc. 2012; 24:36–41. PMID: 22211410.
Article
39. Fabbri C, Luigiano C, Cennamo V, et al. Endoscopic ultrasound-guided transmural drainage of infected pancreatic fluid collections with placement of covered self-expanding metal stents: a case series. Endoscopy. 2012; 44:429–433. PMID: 22382852.
Article
40. Itoi T, Binmoeller KF, Shah J, et al. Clinical evaluation of a novel lumenapposing metal stent for endosonography-guided pancreatic pseudocyst and gallbladder drainage (with videos). Gastrointest Endosc. 2012; 75:870–876. PMID: 22301347.
Article
41. Berzosa M, Maheshwari S, Patel KK, Shaib YH. Single-step endoscopic ultrasonography-guided drainage of peripancreatic fluid collections with a single self-expandable metal stent and standard linear echoendoscope. Endoscopy. 2012; 44:543–547. PMID: 22407382.
Article
42. Penn DE, Draganov PV, Wagh MS, Forsmark CE, Gupte AR, Chauhan SS. Prospective evaluation of the use of fully covered self-expanding metal stents for EUS-guided transmural drainage of pancreatic pseudocysts. Gastrointest Endosc. 2012; 76:679–684. PMID: 22732874.
Article
43. Mangiavillano B, Arcidiacono PG, Masci E, et al. Single-step versus two-step endo-ultrasonography-guided drainage of pancreatic pseudocyst. J Dig Dis. 2012; 13:47–53. PMID: 22188916.
Article
44. Weilert F, Binmoeller KF, Shah JN, Bhat YM, Kane S. Endoscopic ultrasound-guided drainage of pancreatic fluid collections with indeterminate adherence using temporary covered metal stents. Endoscopy. 2012; 44:780–783. PMID: 22791588.
Article
45. Gornals JB, De la Serna-Higuera C, Sánchez-Yague A, Loras C, Sánchez-Cantos AM, Pérez-Miranda M. Endosonography-guided drainage of pancreatic fluid collections with a novel lumen-apposing stent. Surg Endosc. 2013; 27:1428–1434. PMID: 23232994.
Article
46. Binmoeller KF, Weilert F, Shah JN, Bhat YM, Kane S. Endosonography-guided transmural drainage of pancreatic pseudocysts using an exchange-free access device: initial clinical experience. Surg Endosc. 2013; 27:1835–1839. PMID: 23299130.
Article
47. Andrén-Sandberg A, Dervenis C. Pancreatic pseudocysts in the 21st century. Part II: natural history. JOP. 2004; 5:64–70. PMID: 15007187.
48. Jacobson BC, Baron TH, Adler DG, et al. ASGE guideline: the role of endoscopy in the diagnosis and the management of cystic lesions and inflammatory fluid collections of the pancreas. Gastrointest Endosc. 2005; 61:363–370. PMID: 15758904.
Article
49. Varadarajulu S, Bang JY, Phadnis MA, Christein JD, Wilcox CM. Endoscopic transmural drainage of peripancreatic fluid collections: outcomes and predictors of treatment success in 211 consecutive patients. J Gastrointest Surg. 2011; 15:2080–2088. PMID: 21786063.
Article
50. Seifert H, Dietrich C, Schmitt T, Caspary W, Wehrmann T. Endoscopic ultrasound-guided one-step transmural drainage of cystic abdominal lesions with a large-channel echo endoscope. Endoscopy. 2000; 32:255–259. PMID: 10718392.
Article
51. Seifert H, Faust D, Schmitt T, Dietrich C, Caspary W, Wehrmann T. Transmural drainage of cystic peripancreatic lesions with a new large-channel echo endoscope. Endoscopy. 2001; 33:1022–1026. PMID: 11740644.
Article
52. Giovannini M, Bernardini D, Seitz JF. Cystogastrotomy entirely performed under endosonography guidance for pancreatic pseudocyst: results in six patients. Gastrointest Endosc. 1998; 48:200–203. PMID: 9717789.
Article
53. Baron TH. Endoscopic drainage of pancreatic pseudocysts, abscesses and organized (walled-off) necrosis. In : Baron TH, Kozarek RA, Carr-Locke DL, editors. ERCP. Philadelphia: Saunders/Elsevier;2008. p. 475–491.
54. Wiersema MJ. Endosonography-guided cystoduodenostomy with a therapeutic ultrasound endoscope. Gastrointest Endosc. 1996; 44:614–617. PMID: 8934175.
Article
55. Binmoeller KF, Soehendra N. Endoscopic ultrasonography in the diagnosis and treatment of pancreatic pseudocysts. Gastrointest Endosc Clin N Am. 1995; 5:805–816. PMID: 8535629.
Article
56. Puri R, Mishra SR, Thandassery RB, Sud R, Eloubeidi MA. Outcome and complications of endoscopic ultrasound guided pancreatic pseudocyst drainage using combined endoprosthesis and naso-cystic drain. J Gastroenterol Hepatol. 2012; 27:722–727. PMID: 22313377.
Article
57. Zheng M, Qin M. Endoscopic ultrasound guided transgastric stenting for the treatment of traumatic pancreatic pseudocyst. Hepatogastroenterology. 2011; 58:1106–1109. PMID: 21937358.
Article
58. Varadarajulu S, Christein JD, Wilcox CM. Frequency of complications during EUS-guided drainage of pancreatic fluid collections in 148 consecutive patients. J Gastroenterol Hepatol. 2011; 26:1504–1508. PMID: 21575060.
Article
59. Will U, Wanzar C, Gerlach R, Meyer F. Interventional ultrasound-guided procedures in pancreatic pseudocysts, abscesses and infected necroses: treatment algorithm in a large single-center study. Ultraschall Med. 2011; 32:176–183. PMID: 21259182.
60. Talreja JP, Shami VM, Ku J, Morris TD, Ellen K, Kahaleh M. Transenteric drainage of pancreatic-fluid collections with fully covered self-expanding metallic stents (with video). Gastrointest Endosc. 2008; 68:1199–1203. PMID: 19028232.
Article
61. Antillon MR, Bechtold ML, Bartalos CR, Marshall JB. Transgastric endoscopic necrosectomy with temporary metallic esophageal stent placement for the treatment of infected pancreatic necrosis (with video). Gastrointest Endosc. 2009; 69:178–180. PMID: 18582877.
Article
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