Brain Tumor Res Treat.  2013 Apr;1(1):42-44. 10.14791/btrt.2013.1.1.42.

An Intracranial Chondroma with Intratumoral Hemorrhage: A Case Report and Review of the Literature

• Park JH
• Jeun SS

• KMID: 2165222
• DOI: http://doi.org/10.14791/btrt.2013.1.1.42

Abstract

A 55-year-old female presented to the emergency room with a complaint of aphasia. Her initial brain computed tomography scan showed an intracranial hemorrhage in the left frontal area. After surgery, histopathological examination confirmed the diagnosis of a chondroma. Intradural chondroma is a rare, slow growing, benign intracranial neoplasm, but is even rarer in combination with an intratumoral hemorrhage. Chondromas are generally avascular cartilaginous lesions. Our case was thought to be caused by the rupture of abnormally weak vessels derived from the friable tumor. Intradural chondromas may be included in the differential diagnosis of intracranial tumors with acute hemorrhages.

Keyword

Intradural chondroma; Intracranial chondroma; Intratumoral hemorrhage; Tumor bleeding; Chondroma

MeSH Terms

Aphasia
Brain
Brain Neoplasms
Chondroma*
Diagnosis
Diagnosis, Differential
Emergencies
Female
Hemorrhage*
Humans
Intracranial Hemorrhages
Middle Aged
Rupture

Figure

• 

  Fig. 1 Preoperative MRI images show a space-occupying lesion attached to the falx and dura at the left frontal area. A: T2-weighted image. B: T1-weighted image. C: T1-weighted enhanced image. MRI: magnetic resonance imaging.

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  Fig. 2 Postoperative image study. A: The tumor was totally removed according to the postoperative MRI scan. B: A six month follow-up MRI scan showed no evidence of recurrence (both, T1-weighted enhanced image). MRI: magnetic resonance imaging.

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  Fig. 3 Histologic finding of tumor specimen. A: An intracranial tumor, which showed a lobulated growth pattern (×40, H&E). B: Hemorrhagic areas were present inside the tumor (×100, H&E). C: Tumor cells were distributed in the myxoid cartilaginous matrix with eosinophilic cytoplasm and absence of nuclear atypism. A few tumor cells had lacunae (×400, H&E).

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