Clin Endosc.  2016 Mar;49(2):182-186. 10.5946/ce.2015.049.

Endoscopic Submucosal Dissection for Early Gastric Neoplasia Occurring in the Remnant Stomach after Distal Gastrectomy

• Lee JY
• Min BH
• Lee JG
• Noh D
• Lee JH
• Rhee PL
• Kim JJ

• KMID: 2165043
• DOI: http://doi.org/10.5946/ce.2015.049

Abstract

BACKGROUND/AIMS
Endoscopic submucosal dissection (ESD) for tumors occurring in the remnant stomach is technically difficult to perform because of limited working space and severe fibrosis and staples present around the suture line. We aimed to elucidate the feasibility and clinical outcomes of performing ESD for tumors in the remnant stomach.
METHODS
Between December 2007 and January 2013, 18 patients underwent ESD for tumors (six adenomas and 12 differentiated-type early gastric cancers [EGCs]) occurring in the remnant stomach after distal gastrectomy. Clinicopathologic features and clinical outcomes after ESD were retrospectively analyzed.
RESULTS
Two-thirds of the lesions were located on the body, and half were located on the suture line. En bloc resection, R0 resection, and en bloc with R0 resection rates were 88.9%, 100%, and 88.9%, respectively. Curative resection rate for EGC was 91.7%. Perforation occurred in one patient (5.6%) and was successfully managed by endoscopic closure with metallic clips and conservative management. There was no significant bleeding after ESD. During a median follow-up of 47.5 months, no local, metachronous, or extragastric recurrence was seen for either EGC or adenoma lesions.
CONCLUSIONS
ESD is a feasible and effective treatment modality and can be considered a primary intervention for early gastric neoplasia occurring in the remnant stomach.

Keyword

Endoscopic submucosal dissection; Gastric stump; Gastric tumor

MeSH Terms

Adenoma
Fibrosis
Follow-Up Studies
Gastrectomy*
Gastric Stump*
Hemorrhage
Humans
Recurrence
Retrospective Studies
Stomach Neoplasms
Sutures

Figure

• 

  Fig. 1. (A) A 1.5-cm, flat, elevated-type early gastric cancer (arrows) is noted on the suture line (arrowheads) of the lesser curvature of high body in the remnant stomach. (B) Chromoendoscopy with indigo carmine dye. (C) Dissection of the submucosal layer after circumferential incision of the mucosa. Staples (arrowhead) and severe fibrosis are observed around the suture line. (D) The tumor is completely removed by en bloc resection.

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