J Korean Soc Radiol.  2016 May;74(5):335-338. 10.3348/jksr.2016.74.5.335.

Adult-Onset Juvenile Xanthogranuloma of the External Auditory Canal: A Case Report

Affiliations
  • 1Department of Radiology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea. mirachx@naver.com
  • 2Department of Radiology, Kangwon National University College of Medicine, Chuncheon, Korea.
  • 3Department of Radiology, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.
  • 4Department of Pathology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea.

Abstract

Juvenile xanthogranuloma (JXG) is a benign, spontaneously regressing lesion that usually occurs during the first year of life, but may also occur in adulthood. Although the most common presentation of JXG is the cutaneous lesion, it can also manifest in various visceral organs. JXG of the external auditory canal is extremely rare, and there have been only a few reports of those cases in the English literature. In this study, we present a case of pathologically proven JXG that occurred in the external auditory canal with a symptomatic clinical presentation.


MeSH Terms

Ear Canal*
Tomography, X-Ray Computed
Xanthogranuloma, Juvenile*

Figure

  • Fig. 1 An otoscopic image is showing a smooth margined, round soft tissue mass 5 mm in size in the left external auditory canal.

  • Fig. 2 Pre-contrast axial (A) and coronal (B) images of temporal bone CT demonstrating an ovoid soft tissue nodule 5 × 3 mm in size, in the middle of the left external auditory canal, attached to the antero-superior wall.

  • Fig. 3 Microscopic images of the specimen showing foamy histiocytes, Touton giant cells, lymphocytes, and a few eosinophils, consistent with the characteristics of xanthogranuloma; hematoxylin and eosin, × 100 (A) and × 400 (B).


Reference

1. Adamson HG. Society intelligence: The Dermatological Society of London. Br J Dermatol. 1905; 17:222.
2. Helwig EB, Hackney VC. Juvenile xanthogranuloma (nevoxanthoendothelioma). Am J Pathol. 1954; 30:625–626.
3. Hernandez-Martin A, Baselga E, Drolet BA, Esterly NB. Juvenile xanthogranuloma. J Am Acad Dermatol. 1997; 36(3 Pt 1):355–367. quiz 368-369
4. Yoshihama K, Kato Y, Baba Y. Xanthogranuloma of the external auditory canal mimicking a benign tumor: a case report. Case Rep Otolaryngol. 2012; 2012:298089.
5. Lesniak MS, Viglione MP, Weingart J. Multicentric parenchymal xanthogranuloma in a child: case report and review of the literature. Neurosurgery. 2002; 51:1493–1498. discussion 1498
6. Margulis A, Melin-Aldana H, Bauer BS. Juvenile xanthogranuloma invading the muscles in the head and neck: clinicopathological case report. Ann Plast Surg. 2003; 50:425–428.
7. Viswanatha B. Extracanalicular osteoma of the temporal bone. Ear Nose Throat J. 2008; 87:381–383.
8. Woldenberg Y, Nash M, Bodner L. Peripheral osteoma of the maxillofacial region. Diagnosis and management: a study of 14 cases. Med Oral Patol Oral Cir Bucal. 2005; 10:Suppl 2. E139–E142.
9. Heilbrun ME, Salzman KL, Glastonbury CM, Harnsberger HR, Kennedy RJ, Shelton C. External auditory canal cholesteatoma: clinical and imaging spectrum. AJNR Am J Neuroradiol. 2003; 24:751–756.
10. Markou K, Karasmanis I, Vlachtsis K, Petridis D, Nikolaou A, Vital V. Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review. Am J Otolaryngol. 2008; 29:142–146.
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