Ann Dermatol.  2001 Sep;13(3):190-192. 10.5021/ad.2001.13.3.190.

A Case of Verrucous Carcinoma Occurring in Patient with Diabetes Mellitus and Chronic Renal Failure

• Chong YS
• Ahn SW
• Kim MN
• Ro BI
• Song KY

• KMID: 2163893
• DOI: http://doi.org/10.5021/ad.2001.13.3.190

Abstract

Verrucous carcinoma is a slow growing, low grade squamous cell carcinoma, which usually occurs on oropharynx, genitalia and soles. When it occurs on feet, it is known as epithelioma cuniculatum. Epithelioma cuniculatum is characterized by its histologic sinuses and cystic formations in a cuniculate(rabbit burrow-like) pattern. A 59-year-old man was consulted to our department for a well circumscribed, 5 × 5 cm sized, round, hyperkeratotic, verrucous plaque on the right great toe. He suffered from diabetes mellitus for 16 years and was managed by peritoneal dialysis three times a week due to chronic renal failure for last two years. The plaque had gradually increased in size. The biopsy specimen taken from the tumor mass showed chronic ulcerative inflammation with atypical squamous cell proliferation. We herein report a case of verrucous carcinoma occurring in a patient with diabetes melli-t tus and chronic renal failure.

Keyword

Verrucous carcinoma

MeSH Terms

Biopsy
Carcinoma
Carcinoma, Squamous Cell
Carcinoma, Verrucous*
Cell Proliferation
Diabetes Mellitus*
Foot
Genitalia
Humans
Inflammation
Kidney Failure, Chronic*
Middle Aged
Oropharynx
Peritoneal Dialysis
Toes
Ulcer