Korean J Gastroenterol.  2014 Sep;64(3):154-157. 10.4166/kjg.2014.64.3.154.

Adenocarcinoma of Lung Cancer with Solitary Metastasis to the Stomach

• Koh SA
• Lee KH

• KMID: 2160657
• DOI: http://doi.org/10.4166/kjg.2014.64.3.154

Abstract

Although hematogenous metastasis of cancer to the gastrointestinal track is rare, it sometime has been reported in patients with malignant melanoma and breast cancer. However, it is extremely rare for lung cancer to metastasize to the stomach, not to mention solitary gastric metastasis. Herein, the authors report a case of a 69-year-old man who was initially diagnosed with lung cancer with synchronous primary gastric cancer which proved to be lung cancer with solitary gastric metastasis after the operation.

Keyword

Carcinoma; Lung; Stomach; Metastasis

MeSH Terms

Adenocarcinoma/*diagnosis/pathology
Aged
Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Diagnosis, Differential
Endoscopy, Digestive System
Humans
Lung Neoplasms/*diagnosis/drug therapy/pathology
Male
Stomach Neoplasms/*diagnosis/secondary/surgery
Tomography, X-Ray Computed

Figure

• 

  Fig. 1. Esophagogastroduodenoscopy shows convergence of the rugal folds with about 2.5 cm-sized central depression at anterior wall of greater curvature on mid-body.

• 

  Fig. 2. Chest computed tomography shows a 2.2 cm-sized spiculated nodule in right lower lung (A) and multiple calcified mediastinal and right hilar lymph nodes (B).

• 

  Fig. 3. Histologic findings of lung mass biopsy specimen. (A) Moderately differentiated adenocarcinoma of acinar type is observed (H&E, ×100).(B) The tumor cells show a strong positive staining for thyroid transcription factor-1 (×100).

• 

  Fig. 4. Histologic findings of the stomach operation specimen. (A) An undifferentiated diffuse proliferation, suggesting poorly differentiated adenocarcinoma, infiltrating to the submucosa layer with marked lymphovascular invasion is observed (H&E, ×100). (B) The tumor cells show a strong positive staining for thyroid transcription factor-1 (×100).

Reference

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