Korean J Ophthalmol.  2016 Apr;30(2):121-126. 10.3341/kjo.2016.30.2.121.

Obstructive Sleep Apnea in Patients with Branch Retinal Vein Occlusion: A Preliminary Study

Affiliations
  • 1Department of Ophthalmology, CHA Bundang Medical Center, CHA University, Seongnam, Korea. songwk@cha.ac.kr
  • 2Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

PURPOSE
Our study aimed to determine whether obstructive sleep apnea (OSA) is common among branch retinal vein occlusion (BRVO) patients without systemic risk factors using a Watch PAT-100 portable monitoring device.
METHODS
The study participants included consecutive patients with BRVO of less than 3 months duration without any risk factors known to be associated with OSA (diabetes, coronary artery disease, stroke, hematologic diseases, autoimmune disease, etc.) except for hypertension. All patients underwent full-night unattended polysomnography by means of a portable monitor Watch PAT-100 device. The apnea-hypopnea index (AHI) was calculated as the average number of apnea and hypopnea events per hour of sleep, and an AHI score of five or more events was diagnosed as OSA.
RESULTS
Among 19 patients (6 males and 13 females), 42.1% (8 of 19) had an AHI reflective of OSA. In the 13 patients who had no concurrent illness, including hypertension, 30.8% (4 of 13) had positive test results for OSA; three of these patients were ranked as mild OSA, while one had moderate OSA. The OSA group had an average AHI of 12.3 ± 7.8, and the average AHI was 2.0 ± 0.9 in the non-OSA group. Although it was not statistically proven, we found that OSA patients experienced a more severe form of BRVO.
CONCLUSIONS
We found a higher than expected rate of OSA in BRVO patients lacking concomitant diseases typically associated with OSA. Our findings suggest that OSA could be an additional risk factor in the pathogenesis of BRVO or at least a frequently associated condition that could function as a triggering factor.

Keyword

Branch retinal vein occlusion; Hypertension; Obstructive sleep apnea

MeSH Terms

Apnea
Autoimmune Diseases
Coronary Artery Disease
Hematologic Diseases
Humans
Hypertension
Male
Polysomnography
Retinal Vein Occlusion*
Retinal Vein*
Retinaldehyde*
Risk Factors
Sleep Apnea, Obstructive*
Stroke
Retinaldehyde

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