Ann Dermatol.  2004 Mar;16(1):42-44. 10.5021/ad.2004.16.1.42.

Pityriasis Rotunda Associated with Hepatocellular Carcinoma

Abstract

Pityriasis rotunda is an unusual disease characterized by perfectly circular or oval-shaped dyschromic patches with a scaling surface. Histologically, the lesions resemble those of ichthyosis vulgaris. They typically involve the abdomen, the trunk and extremities. The etiology of the disease remains unknown. Pityriasis rotunda has been most commonly associated with tuberculosis, nonlymphoproliferative neoplasms such as hepatocellular carcinoma and gastric carcinoma, and malnutrition. Rarely, hepatic cirrhosis, leprosy, endometriosis, and familial G6PD deficiency can be associated with pityriasis rotunda. We describe here a patient with pityriasis rotunda associated with hepatocellular carcinoma. Pityriasis rotunda can be a presenting sign of hepatocellular carcinoma in the setting of chronic liver cirrhosis.

Keyword

Pityriasis rotunda; Hepatocellular carcinoma

MeSH Terms

Abdomen
Carcinoma, Hepatocellular*
Endometriosis
Extremities
Female
Glucosephosphate Dehydrogenase Deficiency
Humans
Ichthyosis Vulgaris
Leprosy
Liver Cirrhosis
Malnutrition
Pityriasis*
Tuberculosis
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