J Korean Med Sci.
2013 Jan;28(1):164-166. 10.3346/jkms.2013.28.1.164.
A Case of Hypersensitivity to Mosquito Bites without Peripheral Natural Killer Cell Lymphocytosis in a 6-Year-Old Korean Boy
- Affiliations
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- 1Department of Pediatrics, Dongguk University Ilsan Hospital, Goyang, Korea. silbear@dumc.or.kr
- 2Department of Pathology, Dongguk University Ilsan Hospital, Goyang, Korea.
- 3Department of Dermatology, Dongguk University Ilsan Hospital, Goyang, Korea.
- KMID: 2158018
- DOI: http://doi.org/10.3346/jkms.2013.28.1.164
Abstract
- Hypersensitivity to mosquito bites (HMB) is a rare disease characterized by intense skin reactions such as bulla and necrotic ulcerations at bite sites, accompanied by general symptoms such as high-grade fever and malaise occurred after mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer (NK) cell leukemia/lymphoma. We describe here a Korean child who presented with 3-yr history of HMB without natural killer cell lymphocytosis. He has been ill for 6 yr with HMB. Close observation and examination for the development of lymphoproliferative status or hematologic malignant disorders is needed.
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