Ann Dermatol.  2015 Dec;27(6):789-791. 10.5021/ad.2015.27.6.789.

Hydroa Vacciniforme-Like Eruption Associated with Epstein-Barr Virus Infection in an Older Adult

Affiliations
  • 1Department of Dermatology, Ajou University School of Medicine, Suwon, Korea. maychan@ajou.ac.kr
  • 2Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Adult*
Herpesvirus 4, Human*
Humans

Figure

  • Fig. 1 Multiple erythematous crusted papulopustules are observed, with ulcers on both cheeks and the forehead. Arrows indicate the biopsy sites: one pustule and one papule on the forehead.

  • Fig. 2 Small to medium-sized atypical lymphoid cells infiltrate the perivascular and periadenexal areas throughout the entire dermis (hematoxylin and eosin staining; A: ×40, B: ×200). The atypical cells are positive for (C) CD3, focally positive for (D) CD8, and positive for (E) in situ hybridization for Epstein-Barr virus (EBV)-encoded RNAs (×100).


Reference

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2. Cho KH, Lee SH, Kim CW, Jeon YK, Kwon IH, Cho YJ, et al. Epstein-Barr virus-associated lymphoproliferative lesions presenting as a hydroa vacciniforme-like eruption: an analysis of six cases. Br J Dermatol. 2004; 151:372–380.
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3. Park BM, Ahn JS, Lee JB, Won YH, Yun SJ. Chronic active Epstein-Barr virus infection-associated hydroa vacciniformelike eruption and Behçet's-like orogenital ulcers. Dermatology. 2013; 226:212–216.
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4. Nomura H, Egami S, Kasai H, Mori M, Yokoyama T, Fujimoto A, et al. An elderly patient with chronic active Epstein-Barr virus infection with severe hydroa vacciniforme-like eruptions associated with αβT-cell proliferation. J Dermatol. 2014; 41:360–362.
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5. Eminger LA, Hall LD, Hesterman KS, Heymann WR. Epstein-Barr virus: dermatologic associations and implications: part II. Associated lymphoproliferative disorders and solid tumors. J Am Acad Dermatol. 2015; 72:21–34.
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