Ann Dermatol.  2011 Oct;23(Suppl 2):S247-S249. 10.5021/ad.2011.23.S2.S247.

A Case of Becker's Nevus with Osteoma Cutis

• Park SB
• Song BH
• Park EJ
• Kwon IH
• Kim KH
• Kim KJ

• KMID: 2156801
• DOI: http://doi.org/10.5021/ad.2011.23.S2.S247

Abstract

Becker's nevus is a relatively common acquired focal epidermal melanotic hypermelanosis usually found in the region of the shoulder girdle of young men. Various skeletal malformations and cutaneous dermatoses have been reported in Becker's nevus. Osteoma cutis is a rare disorder characterized by compact bone formation in the dermis or subcutaneous tissue. Secondary ossification on nevi has been reported, but not with Becker's nevus. Herein, we report a case of Becker's nevus with accompanying osteoma cutis in an 18-year-old female.

Keyword

Bone neoplasm; Nevus; Osteoma; Pigmented

MeSH Terms

Adolescent
Bone Diseases, Metabolic
Bone Neoplasms
Dermis
Female
Humans
Hyperpigmentation
Male
Nevus
Ossification, Heterotopic
Osteogenesis
Osteoma
Shoulder
Skin Diseases
Skin Diseases, Genetic
Subcutaneous Tissue
Bone Diseases, Metabolic
Ossification, Heterotopic
Skin Diseases, Genetic

Figure

• 

  Fig. 1 Localized light-brown colored reticular patches with hair on the right upper arm.

• 

  Fig. 2 (A) Acanthosis, elongation of the rete ridge, and hyperpigmentation of the basal layer (H&E, ×40). (B) Nodular, whorl-like pattern of matrix and spicule of bone surrounded by osteoblasts in the dermis (H&E, ×200). (C) The bony tissue is composed of osteocytes and osteoblasts showing a lamellar structure (H&E, ×400).

Reference

1. Becker SW. Concurrent melanosis and hypertrichosis in distribution of nevus unis lateris. Arch Derm Syphilol. 1949. 60:155–160.

2. Kim YJ, Kim MY, Kim HO, Park YM, Kang H. Becker's nevus with underlying neurofibroma. Korean J Dermatol. 2004. 42:1039–1041.

3. Glinick SE, Alper JC, Bogaars H, Brown JA. Becker's melanosis. Associated abnormalities. J Am Acad Dermatol. 1983. 9:509–514.

4. Ragsdale BD. Elder DE, Elnitsas R, Johonson BL, Murphy GF, editors. Tumors with fatty, muscular, osseous, and cartilaginous differentiation. Lever's histopathology of the skin. 2004. 9th ed. Philadelphia: Lippincott-Raven;1089–1091.

5. Weedon D. Skin pathology. 1997. . New York: Churchill Livingstone Inc;675.

6. Person JR, Longcope C. Becker's nevus: an androgen-mediated hyperplasia with increased androgen receptors. J Am Acad Dermatol. 1984. 10:235–238.

7. Formigon M, Alsina MM, Mascaro JM. Becker's nevus and ipsilateral breast hypoplasia; androgen receptor study in two patients. Arch Dermatol. 1992. 128:992–993.

8. Happle R, Koopman RJ. Becker nevus syndrome. Am J Med Genet. 1997. 68:357–361.

9. Happle R. Mosaicism in human skin. Understanding the patterns and mechanisms. Arch Dermatol. 1993. 129:1460–1470.

10. Danarti R, König A. Becker's nevus syndrome revisited. J Am Acad Dermatol. 2004. 51:965–969.

11. Kim HW, Seo YJ, Lee JH, Park JK, Nam IH. Treatment of Becker's nevus using a Q-switched ND:YAG laser. Korean J Dermatol. 2004. 42:392–397.

12. Orlow SJ, Watsky KL, Bolognia JL. Skin and bones. II. J Am Acad Dermatol. 1991. 25:447–462.

13. Burgdorf W, Nasemann T. Cutaneous osteomas: a clinical and histopathological review. Arch Dermatol Res. 1977. 260:121–135.