Ann Dermatol.  2011 Oct;23(Suppl 2):S231-S234. 10.5021/ad.2011.23.S2.S231.

Nevus Sebaceous Accompanying Secondary Neoplasms and Unique Histopathologic Findings

• Kim JH
• Park HY
• Ahn SK

• KMID: 2156797
• DOI: http://doi.org/10.5021/ad.2011.23.S2.S231

Abstract

Nevus sebaceous (NS) is a type of classical nevus or congenital malformation that is often present at birth and commonly involves the scalp or face. The lesion usually presents as a linear, yellow, hairless, and verrucous plaque. It has been well-established that several benign and malignant tumors can develop from the NS; however, there have been no reports about ectopic fat cells in the dermis, and cornoid lamella arising from the NS. We report a case of NS on the scalp with accompanying unusual histopathologic findings.

Keyword

Cornoid lamella; Ectopic fat cell; Nevus sebaceous; Secondary neoplasms

MeSH Terms

Adipocytes
Dermis
Nevus
Parturition
Scalp

Figure

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  Fig. 1 A solitary 3×5 cm yellow verrucous plaque in the scalp.

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  Fig. 2 Histopathology of the yellow, verrucous plaque. Hyperkeratosis, irregular acanthosis, and papillomatosis were present in the epidermis. Incompletely differentiated hair structures were in the dermis (H&E, ×12.5).

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  Fig. 3 (A) Cystic invagination extended downward from the epidermis (H&E, ×40), which was diagnosed as a syringocystadenoma papilliferum. (B) There was a parakeratotic column overlying the trichoblastoma like-lesion, resembling the cornoid lamella of porokeratosis (H&E, ×40). (C) There were fat cells in upper dermis (H&E, ×40). (D) The basaloid epithelial proliferation showed PAS negative finding (PAS, ×100).

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