Ann Dermatol.  2011 Oct;23(Suppl 2):S175-S178. 10.5021/ad.2011.23.S2.S175.

Syringocystadenoma Papilliferum in Co-existence with Tubular Apocrine Adenoma on the Calf

  • 1Department of Dermatology, Korea University College of Medicine, Seoul, Korea.


Syringocystadenoma papilliferum (SCAP) occurs singly or in association with other tumors. Although it is rare, the association of tubular apocrine adenoma (TAA) with SCAP in the background of nevus sebaceous (NS) on the scalp is well documented. However, the co-existence of these two tumors without background of NS has not been reported on the extremities. We report a case of SCAP associated with TAA on the calf without pre-existing NS in an adult.


Nevus sebaceous; Syringocystadenoma papilliferum; Tubular apocrine adenoma

MeSH Terms



  • Fig. 1 1.3×1.2 cm-sized itchy, errythematous, lobulated nodule with a partially crusted surface on the left calf area.

  • Fig. 2 Whole-mounted view of the lesion: Tumor is composed of two histologically distinct parts. The upper part shows syringocystadenoma papilliferum and the lower part shows tubular apocrine adenoma (H&E, scanning view).

  • Fig. 3 Findings of the upper section of the lesion. Cystic invagination lined by glandular epithelium with papillary projections. The cystic invagination is connected to the skin surface through the infundibular epithelium (H&E, A: ×40, B: ×100).

  • Fig. 4 Findings of the lower part of the lesion. Variable sized tubular structures are seen. Amorphous material containing cellular fragments was observed in several lumina (H&E, A: ×40, B: ×100).


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