Ann Dermatol.  2009 Nov;21(4):416-418. 10.5021/ad.2009.21.4.416.

Dermatofibrosarcoma Protuberans Arising froma Burn Scar

• Seo JK
• Cho KJ
• Kang JH
• Lee D
• Sung HS
• Hwang SW

• KMID: 2156510
• DOI: http://doi.org/10.5021/ad.2009.21.4.416

Abstract

Malignant neoplasms arising in burn scars are well known. In previous literature, 25 cases of burn scar sarcomas were reported. However, dermatofibrosarcoma protuberans is very rare and only two cases have been reported. A 43-year-old Korean man presented with multiple erythematous clustered plaques and nodules and a skin-colored subcutaneous mass on the chest after a severe burn injury at the age of 8 years. A biopsy specimen revealed dermatofibrosarcoma protuberans. The tumor was excised widely to include the surrounding burn scar. Herein, we report this third case of dermatofibrosarcoma protuberans arising from a burn scar.

Keyword

Burn scar; Dermatofibrosarcoma protuberans

MeSH Terms

Adult
Biopsy
Burns
Cicatrix
Dermatofibrosarcoma
Humans
Sarcoma
Thorax
Dermatofibrosarcoma

Figure

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  Fig. 1 Multiple erythematous clustered plaques and nodules and a skin-colored subcutaneous mass on the chest (inset: close up view).

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  Fig. 2 (A) Histological examination of the erythematous nodule demonstrated dense cellular infiltration with storiform pattern distribution (H&E, ×40). Inset: Uniform, plump spindle cells with honeycomb-like appearance (H&E, ×200). (B) Densely packed spindle cells arranged in interlacing fascicles (H&E, ×100). (C) Immunohistologic examination for CD34 showed spindle-shaped cells stained strongly positive (CD34, ×200). (D) S-100 protein staining of the spindle-shaped cells was negative (S-100, ×200).

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