Korean J Med.  2016 Mar;90(3):274-279. 10.3904/kjm.2016.90.3.274.

Biopsy-Proven Dermatomyositis with Normal Creatine Kinase

• Kwon SH
• Eun JS
• Lee ES
• Kang YM
• Nam EJ

• KMID: 2155947
• DOI: http://doi.org/10.3904/kjm.2016.90.3.274

Abstract

Dermatomyositis (DM) is an idiopathic inflammatory myopathy (IIM) characterized by skeletal muscle inflammation and typical skin manifestations. Creatine kinase (CK) has traditionally been considered to be the most useful serum enzyme for the diagnosis and assessment of adult patients with IIM. To our knowledge, there has been no reported case of biopsy-proven DM without CK elevation in Korea, to date. Panniculitis is an uncommon cutaneous manifestation in adult patients with DM. A search of the PubMed database reveals fewer than 30 reported cases of panniculitis in adult patients with DM. Here, we report a case of a 42-year-old female who was diagnosed with biopsy-proven DM with normal serum CK levels and panniculitis.

Keyword

Dermatomyositis; Creatine kinase; Panniculitis

MeSH Terms

Adult
Creatine Kinase*
Creatine*
Dermatomyositis*
Diagnosis
Female
Humans
Inflammation
Korea
Muscle, Skeletal
Myositis
Panniculitis
Skin Manifestations
Creatine
Creatine Kinase