Gut Liver.
2015 May;9(3):318-331. 10.5009/gnl14344.
Gut Microbiota as Potential Orchestrators of Irritable Bowel Syndrome
- Affiliations
-
- 1Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. magnus.simren@medicine.gu.se
- 2Department of Microbiology and Immunology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
- KMID: 2155639
- DOI: http://doi.org/10.5009/gnl14344
Abstract
- Irritable bowel syndrome (IBS) is a multifactorial functional disorder with no clearly defined etiology or pathophysiology. Modern culture-independent techniques have improved the understanding of the gut microbiota's composition and demonstrated that an altered gut microbiota profile might be found in at least some subgroups of IBS patients. Research on IBS from a microbial perspective is gaining momentum and advancing. This review will therefore highlight potential links between the gut microbiota and IBS by discussing the current knowledge of the gut microbiota; it will also illustrate bacterial-host interactions and how alterations to these interactions could exacerbate, induce or even help alleviate IBS.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Pathogenic role of the gut microbiota in gastrointestinal diseases
- Gut Microbiota in Health and Probiotics in Functional Bowel Disease
- Alteration of Fecal Microbiota in Patients With Postinfectious Irritable Bowel Syndrome
- Microflora Modulation of Motility
- Irritable Bowel Syndrome, Gut Microbiota and Probiotics
