J Korean Med Sci.  2015 May;30(5):662-665. 10.3346/jkms.2015.30.5.662.

Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits

Affiliations
  • 1Division of Infectious Diseases, Konyang University College of Medicine, Daejeon, Korea. rhayjo@hanmail.net
  • 2Division of Bacterial Respiratory Infections, Centers for Infectious Diseases, National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongwon, Korea.

Abstract

We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no definite septicemia or meningitis. Neisseria meningitidis serogroup W-135 was detected in the serum and cerebrospinal fluid (CSF) of all patients by real-time polymerase chain reaction. In the one case of mortality, two strains were isolated from the patient's blood and CSF. Using multilocus sequence typing analysis, these strains were identified as a novel sequence type, ST-8912. Special attention is required for the meningococcal disease in military camp because the military personnels are in high risk of contact transmission.

Keyword

Meningococcal Infections; Neisseria meningitides, Serogroup W-135; Military Personnel

MeSH Terms

DNA, Bacterial/blood/cerebrospinal fluid
Electrophoresis, Gel, Pulsed-Field
Humans
Male
Meningitis/complications/*diagnosis/microbiology
Military Personnel
Multilocus Sequence Typing
Neisseria meningitidis, Serogroup W-135/genetics/*isolation & purification
Real-Time Polymerase Chain Reaction
Sepsis/complications/*diagnosis/microbiology
Young Adult
DNA, Bacterial
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