Korean J Gastroenterol.  2014 May;63(5):321-324. 10.4166/kjg.2014.63.5.321.

Disappearance of Intrahepatic Bile Duct Hepatocellular Carcinoma after Endoscopic Retrograde Cholangiopancreatography and Transarterial Chemoinfusion: A Case Report

• Cho YY
• Lee SH
• Lee JW
• Park JM
• Ryu JK
• Kim YT
• Yoon CJ
• Kim H

• KMID: 2155332
• DOI: http://doi.org/10.4166/kjg.2014.63.5.321

Abstract

Invasion of the bile duct by hepatocellular carcinoma (HCC), which is called intrahepatic bile duct HCC, is rare and has a poor prognosis. Early diagnosis and surgical resection is important for treatment. A 58-year-old man who underwent hepatic resection for HCC 4 years ago and received transarterial chemoembolization (TACE) 2 years after the operation for recurred HCC presented with jaundice. CT scan revealed a tumor in the common bile duct without intrahepatic lesion. Therefore, ERCP was done to perform biopsy and biliary drainage. Histological examination was compatible with hepatocellular carcinoma. However, the tumor could not be visualized at angiography and thus, only transarterial chemoinfusion was performed without embolization. The tumor had disappeared on follow-up CT scan, and the patient has been disease free for 23 months without evidence of recurrence. Herein, we report a case of intrahepatic bile duct HCC which disappeared after ERCP.

Keyword

Hepatocellular carcinoma; Intrahepatic bile duct hepatocellular carcinoma; Icteric type hepatoma

MeSH Terms

Antibiotics, Antineoplastic/therapeutic use
Bile Duct Neoplasms/diagnosis/pathology/secondary/*therapy
Bile Ducts, Intrahepatic
Carcinoma, Hepatocellular/*diagnosis/pathology
Cholangiopancreatography, Endoscopic Retrograde
Doxorubicin/therapeutic use
Embolization, Therapeutic
Ethiodized Oil/therapeutic use
Humans
Jaundice/etiology
Liver Neoplasms/*diagnosis/pathology
Male
Middle Aged
Neoplasm Recurrence, Local
Stents
Tomography, X-Ray Computed
Treatment Outcome
Antibiotics, Antineoplastic
Doxorubicin
Ethiodized Oil

Figure

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  Fig. 1. Coronal view of the CT scan shows a well enhancing tumor in the common bile duct (arrow).

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  Fig. 2. Cholangiogram shows an obstructive mass in the common bile duct.

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  Fig. 3. Histopathologic examination is compatible with hepatocellular carcinoma (H&E, ×100).

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  Fig. 4. Coronal view of the follow-up CT scan shows disappearance of common bile duct tumor after endoscopic retrograde biliary drainage removal.

Reference

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