J Korean Soc Radiol.  2016 Mar;74(3):199-203. 10.3348/jksr.2016.74.3.199.

Multiple Solitary Plasmacytomas Arising in the Posterior Mediastinum and Sternum: A Case Report

• Lee S
• Kang MJ
• Kim JH
• Jeong MJ
• Kim SH
• Kim JY
• Lee JH
• Bae KE
• Kang TK

• KMID: 2155281
• DOI: http://doi.org/10.3348/jksr.2016.74.3.199

Abstract

Multiple solitary plasmacytoma is very rare disease, which occurs in multiple sites of soft tissue, bone or both without multiple myeloma. Almost 80-90% of extramedullary plasmacytomas develop in the head and neck area. Involvement of the mediastinum is extremely rare. A few cases of mediastinal plasmacytoma have been reported, and to the best of our knowledge, there is only one previous report of multiple plasmacytomas involving the posterior mediastinum. Herein, we describe an unusual case of multiple solitary plasmacytomas in a 67-year-old male involving the posterior mediastinum and sternum without evidence of bone marrow involvement.

MeSH Terms

Aged
Bone and Bones
Bone Marrow
Head
Humans
Male
Mediastinum*
Multiple Myeloma
Neck
Plasmacytoma*
Rare Diseases
Sternum*

Figure

• 

  Fig. 1 Plain radiograph and chest CT scan in 67-year-old man with multiple solitary plasmacytomas. Plain radiograph (A) shows thickening of the bilateral paravertebral stripe (black arrows) and bilateral pleural effusion (white arrows). Pre-contrast (B) and post-contrast chest CT (C) images show a heterogeneously enhanced soft tissue mass (white arrows) in the posterior mediastinum at T10 level. Mass encases the abdominal aorta and intercostal arteries (black arrowheads) without definite evidence of invasion. Esophagus (white arrowhead) is replaced anteriorly. Delayed phase of abdominal CT (D) image shows gradual and heterogenous enhancement. Post-contrast CT (E) image shows a round shape osteolytic lesion with sclerotic rim (arrow) in the manubrium of the sternum.

• 

  Fig. 2 PET-CT scan in 67-year-old man with multiple solitary plasmacytomas. PET-CT scan shows 18F-FDG hot uptake in the posterior mediastinum (maxSUV 4.6), T10 vertebral body (maxSUV 3.9) and sternal mass (maxSUV 4.4). It also shows hot uptake in the T8 (maxSUV 5.7) and L3 (maxSUV 3.8) vertebrae (not shown). FDG = fluorodeoxyglucose, maxSUV = maximum standardized uptake value, PET-CT = positron emission tomography-computed tomography

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