Obstet Gynecol Sci.  2016 Jan;59(1):45-49. 10.5468/ogs.2016.59.1.45.

Vasomotor symptoms and the homeostatic model assessment of insulin-resistance in Korean postmenopausal women

• Kwon DH
• Lee JH
• Ryu KJ
• Park HT
• Kim T

• KMID: 2152643
• DOI: http://doi.org/10.5468/ogs.2016.59.1.45

Abstract

The aim of this cross-sectional study was to evaluate the association between vasomotor symptoms (VMS) and insulin resistance, which can be postulated by the homeostatic model assessment (HOMA) index. This study involved 1,547 Korean postmenopausal women (age, 45 to 65 years) attending a routine health check-up at a single institution in Korea from January 2010 to December 2012. A menopause rating scale questionnaire was used to assess the severity of VMS. The mean age of participants was 55.22+/-4.8 years and 885 (57.2%) reported VMS in some degree. The mean HOMA index was 1.79+/-0.96, and the HOMA index increased with an increase in severity of VMS (none, mild, moderate and severe) in logistic regression analysis (beta=0.068, t=2.665, P =0.008). Insulin resistance needs to be considered to understand the linkage between VMS and cardiometabolic disorders.

Keyword

Homeostatic model assessment index; Hot flush; Insulin resistance; Menopause; Vasomotor symptoms

MeSH Terms

Cross-Sectional Studies
Female
Humans
Insulin Resistance
Korea
Logistic Models
Menopause

Figure

• 

  Fig. 1 Trends in homeostatic model assessment (HOMA) index based on the severity of vasomotor symptoms (VMS). Statistical analyses for linear trends were conducted using univariate linear regression analysis method.

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