J Korean Diabetes.  2015 Sep;16(3):182-188. 10.4093/jkd.2015.16.3.182.

Obstetrical Management of Gestational Diabetes Mellitus

Affiliations
  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Korea. mykimdr@gmail.com

Abstract

Gestational diabetes mellitus (GDM) is traditionally defined as newly onset or detected carbohydrate intolerance during pregnancy. Unprotected exposure to high glucose levels during pregnancy is related to adverse pregnancy outcomes including fetal demise and intrauterine growth restriction associated with placental insufficiency. The most common complications related to GDM comprise macrosomia, shoulder dystocia, brachial plexus palsy, intrauterine fetal death and preeclampsia, polyhydramnios, preterm delivery, and increased cesarean section rate. Moreover, GDM may increase the chance of GDM recurrence in a subsequent pregnancy, impaired glucose tolerance or type 2 DM, and obesity or impaired glucose tolerance in the offspring. Therefore, proper obstetrical management and glucose control are always challenging and important. The aim of this article is to discern: 1) obstetric complications related to GDM diagnosed after pregnancy, 2) various methods of fetal surveillance, 3) proper timing for delivery and mode of delivery, 4) postpartum management for GDM patients and neonates, and 5) preconceptional counseling prior to a possible subsequent pregnancy.

Keyword

Gestational diabetes; Obstetrics; Preconception; Pregnancy complication

MeSH Terms

Brachial Plexus
Cesarean Section
Counseling
Diabetes, Gestational*
Dystocia
Female
Fetal Death
Glucose
Humans
Infant, Newborn
Obesity
Obstetrics
Paralysis
Placental Insufficiency
Polyhydramnios
Postpartum Period
Pre-Eclampsia
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Recurrence
Shoulder
Glucose

Reference

References

1. Statistics Korea. Birth statistics 2013 (Confirmation). Available from:. http://kostat.go.kr/portal/korea/kor_nw/2/1/index.board?bmode=read&aSeq=329402. (updated 2014 Aug 26).
2. Han YJ. Cheil index of pregnant women: Advanced maternal age. Department of maternal fetal medicine, Cheil General Hospital. Available from:. http://www.cheilmc.co.kr/. (updated 2015 Feb 16).
3. Committee on Practice Bulletins–Obstetrics. Practice Bulletin No. 137: Gestational diabetes mellitus. Obstet Gynecol. 2013; 122:406–16.
4. Rossi AC, Mullin P, Prefumo F. Prevention, management, and outcomes of macrosomia: a systematic review of literature and metaanalysis. Obstet Gynecol Surv. 2013; 68:702–9.
5. Kjos SL, Buchanan TA. Gestational diabetes mellitus. N Engl J Med. 1999; 341:1749–56.
Article
6. Hawkins JS, Casey BM. Labor and delivery management for women with diabetes. Obstet Gynecol Clin North Am. 2007; 34:323–34. x.
Article
7. Vitoratos N, Vrachnis N, Valsamakis G, Panoulis K, Creatsas G. Perinatal mortality in diabetic pregnancy. Ann N Y Acad Sci. 2010; 1205:94–8.
Article
8. Dudley DJ. Diabetic-associated stillbirth: incidence, pathophysiology, and prevention. Obstet Gynecol Clin North Am. 2007; 34:293–307. ix.
Article
9. Sibai BM, Ross MG. Hypertension in gestational diabetes mellitus: pathophysiology and longterm consequences. J Matern Fetal Neonatal Med. 2010; 23:229–33.
Article
10. Thiebaugeorges O, Guyard-Boileau B. Obstetrical care in gestational diabetes and management of preterm labour. Diabetes Metab. 2010; 36:672–81.
Article
11. McCance DR. Pregnancy and diabetes. Best Pract Res Clin Endocrinol Metab. 2011; 25:945–58.
Article
12. Kjos SL. After pregnancy complicated by diabetes: postpartum care and education. Obstet Gynecol Clin North Am. 2007; 34:335–49. x.
Article
13. Damm P, Mathiesen ER, Petersen KR, Kjos S. Contraception after gestational diabetes. Diabetes Care. 2007; 30(Suppl 2):S236–41.
Article
14. American Diabetes Association. Standards of medical care in diabetes–2013. Diabetes Care. 2013; 36(Suppl 1):S11–66.
15. Landon MB, Gabbe SG. Gestational diabetes mellitus. Obstet Gynecol. 2011; 118:1379–93.
Article
16. American Diabetes Association. Preconception care of women with diabetes. Dibetes Care. 2004; 27(Suppl 1):S76–8.
17. ACOG Committee on Practice Bulletins. ACOG Practice Bulletin. Clinical management guidelines for obstetrician-gynecologists. Number 60, March 2005. Pregestational diabetes mellitus. Obstet Gynecol. 2005; 105:675–85.
18. Thung SF, Landon MB. Fetal surveillance and timing of delivery in pregnancy complicated by diabetes mellitus. Clin Obstet Gynecol. 2013; 56:837–43.
Article
19. Kjos SL, Leung A, Henry OA, Victor MR, Paul RH, Medearis AL. Antepartum surveillance in diabetic pregnancies: predictors of fetal distress in labor. Am J Obstet Gynecol. 1995; 173:1532–9.
Article
20. Graves CR. Antepartum fetal surveillance and timing of delivery in the pregnancy complicated by diabetes mellitus. Clin Obstet Gynecol. 2007; 50:1007–13.
Article
21. Jazayeri A, Heffron JA, Phillips R, Spellacy WN. Macrosomia prediction using ultrasound fetal abdominal circumference of 35 centimeters or more. Obstet Gynecol. 1999; 93:523–6.
Article
22. American College of Obstetricians and Gynecologists. ACOG committee opinion no. 560: Medically indicated late-preterm and early-term deliveries. Obstet Gynecol. 2013; 121:908–10.
23. Garabedian C, Deruelle P. Delivery (timing, route, peripartum glycemic control) in women with gestational diabetes mellitus. Diabetes Metab. 2010; 36:515–21.
Article
24. Ouzounian JG. Risk factors for neonatal brachial plexus palsy. Semin Perinatol. 2014; 38:219–21.
Article
25. Maso G, Piccoli M, Parolin S, Restaino S, Alberico S. Diabetes in pregnancy: timing and mode of delivery. Curr Diab Rep. 2014; 14:506.
Article
Full Text Links
  • JKD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr