Transl Clin Pharmacol.  2015 Jun;23(1):15-20. 10.12793/tcp.2015.23.1.15.

Clinical pharmacology review for primary health care providers: II. Steroids

Affiliations
  • 1Department of Clinical Pharmacology and Therapeutics, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul 137-701, Korea. waystolove@catholic.ac.kr

Abstract

Primary health care providers play a critical role in maintaining public health, and the appropriate prescription of pharmaceutical products is a major component of their practice. This series of articles entitled 'Clinical Pharmacology Review for Primary Health Care Providers' is intended to help primary health care providers select more appropriate prescriptions for frequently used drugs based on up-to-date information. We expect that this effort will contribute to improvements in public health and diminish unnecessary drug use.

Keyword

glucocorticoid; topical agent; systemic steroid; drug interaction; adverse effect

MeSH Terms

Drug Interactions
Pharmaceutical Preparations
Pharmacology
Pharmacology, Clinical*
Prescriptions
Primary Health Care*
Public Health
Steroids*
Pharmaceutical Preparations
Steroids

Reference

References

1. Chrousos GP. Adrenocorticosteroids & adrenocortical antagonists. In: Katzung B & Trevor A (eds) Basic and Clinical Pharmacology. 13th ed.Mc-Grow-Hill education, Columbus;2015. p. 680–695.
2. Falkenstein E, Tillmann HC, Christ M, Feuring M, Wehling M. Multiple actions of steroid hormones–a focus on rapid, nongenomic effects. Pharmacol Rev. 2000; 52:513–556.
3. Allen DB. Effects of inhaled steroids on growth, bone metabolism and adrenal function. Expert Rev Respir Med. 2007; 1:65–74. doi: 10.1586/17476 348.1.1.65.
Article
4. Aubert-Wastiaux H, Moret L, Le Rhun A, Fontenoy AM, Nguyen JM, Leux C, et al. Topical corticosteroid phobia in atopic dermatitis: a study of its nature, origins and frequency. Br J Dermatol. 2011; 165:808–814. doi: 10.11 11/j.1365-2133.2011.10449.x.
5. Aulakh R, Singh S. Strategies for minimizing corticosteroid toxicity: a review. Indian J Pediatr. 2008; 75:1067–1073. doi: 10.1007/s12098-008-0211-6.
6. Buchman AL. Side effects of corticosteroid therapy. J Clin Gastroenterol. 2001; 33:289–294.
Article
7. Czock D, Keller F, Rasche FM, Häussler U. Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids. Clin Pharmacokinet. 2005; 44:61–98.
Article
8. Derendorf H, Hochhaus G, Rohatagi S, Möllmann H, Barth J, Sourgens H, et al. Pharmacokinetics of triamcinolone acetonide after intravenous, oral, and inhaled administration. J Clin Pharmacol. 1995; 35:302–305.
Article
9. Kubota K, Lo ES, Huttinot G, Andersen PH, Maibach HI. Plasma concentrations of betamethasone after topical application of betamethasone 17-valerate: comparison with oral administration. Br J Clin Pharmacol. 1994; 37:86–88.
Article
10. Barnes PJ. Mechanisms and resistance in glucocorticoid control of inflammation. J Steroid Biochem Mol Biol. 2010; 120:76–85. doi: 10.1016/j.js-bmb.2010.02.018.
Article
11. Garg R, Adler GK. Pharmacology of the adrenal cortex. In: Golan DE, Tashjian AH Jr., Armstrong EJ, Armstrong AW (eds) Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. 3rd ed.LWW, Philadelphia;2011. p. 489–504.
12. van der Velden VH. Glucocorticoids: mechanisms of action and antiinflammatory potential in asthma. Mediators Inflamm. 1998; 7:229–237.
Article
13. Laudenbach JM, Epstein JB. Treatment strategies for oropharyngeal candidiasis. Expert Opin Pharmacother. 2009; 10:1413–1421. doi: 10.1517/14 656560902952854.
Article
14. Kaur M, Chivers JE, Giembycz MA, Newton R. Long-acting beta2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airway epithelial and smooth muscle cells. Mol Pharmacol. 2008; 73:203–214.
15. Barnes PJ. Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids. Eur Respir J. 2002; 19:182–191.
16. Robertson DB, Maibach HI. Dermatologic pharmacology. In: Katzung B & Trevor A (eds) Basic and Clinical Pharmacology. 13th ed.McGrow-Hill education, Columbus;2015. p. 1033–1051.
17. Lemos MC, Correr WR, da Silva de Avó LR, Germano CM, Kurachi C, Polikarpov I, et al. Fluorescence spectroscopy as a tool to detect and evaluate glucocorticoid-induced skin atrophy. Lasers Med Sci. 2012; 27:1059–1065. doi: 10.1007/s10103-011-1045-4.
Article
18. Avioli LV. Glucocorticoid effects on statural growth. Br J Rheumatol. 1993; 32:S27–S30.
Article
19. Simon D. Management of growth retardation in juvenile idiopathic arthritis. Horm Res. 2007; 68:S122–S125. doi: 10.1159/000110605.
Article
20. Silbermann M, Maor G. Mechanisms of glucocorticoid-induced growth retardation: impairment of cartilage mineralization. Acta Anat (Basel). 1978; 101:140–149.
Article
21. Andrew R, Gale CR, Walker BR, Seckl JR, Martyn CN. Glucocorticoid metabolism and the metabolic syndrome: associations in an elderly cohort. Exp Clin Endocrinol Diabetes. 2002; 110:284–290.
Article
22. Weinstein RS. Glucocorticoid-Induced bone disease. N Engl J Med. 2011; 365:62–70. doi: 10.1056/NEJMcp1012926.
Article
23. Stanbury RM, Graham EM. Systemic corticosteroid therapy–side effects and their management. Br J Ophthalmol. 1998; 82:704–708.
Article
Full Text Links
  • TCP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr