Ann Rehabil Med.  2015 Aug;39(4):645-648. 10.5535/arm.2015.39.4.645.

Myotonic Dystrophy Type 1 Complicated With Peripheral Arterial Occlusive Disease: A Case Report

• Lee DH
• Park DS
• Kim DH
• Lee SH
• Cho HM

• KMID: 2148238
• DOI: http://doi.org/10.5535/arm.2015.39.4.645

Abstract

Myotonic dystrophy (MD) is the most common adult muscular dystrophy characterized by multi-systemic clinical manifestations involving the brain, smooth muscle, cardiovascular and endocrine systems. However, peripheral arterial occlusive disease (PAOD) is an uncommon presentation of MD type 1 (DM1), which has not been reported in recent literature. A 53-year-old female, previously confirmed as DM1, presented with vague claudication of both lower limbs. The diagnosis of PAOD based on results of ankle-brachial index, ultrasonography, and abdominal computed tomography angiography studies was followed by aortobifemoral artery bypass surgery. Although the arterial patency was restored after the operation, she did not recover from post-operative respiratory complications. Screening of PAOD is necessary for DM1 with general risk factors of occlusive arteriopathy. However, surgery should be reserved for the most severe cases.

Keyword

Myotonic dystrophy; Peripheral arterial occlusive disease

MeSH Terms

Adult
Angiography
Ankle Brachial Index
Arterial Occlusive Diseases*
Arteries
Brain
Diagnosis
Endocrine System
Female
Humans
Lower Extremity
Mass Screening
Middle Aged
Muscle, Smooth
Muscular Dystrophies
Myotonic Dystrophy*
Risk Factors
Ultrasonography

Figure

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  Fig. 1 Ankle-brachial index (ABI) values were 0.09 on right side and 0.42 on left side.

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  Fig. 2 Ultrasonography on lower extremity showed decreased blood flow at left dorsalis pedis artery (A) and right dorsalis pedis artery (B).

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  Fig. 3 Three-dimensional reconstructed abdomen computed tomography angiography showed tapering occlusion in the distal abdominal aorta at 3.5 cm below the renal artery (A). Postoperative finding shows patent lumen at operation site of bypass arterial graft (B).

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