Korean J Gastrointest Endosc.  2002 Mar;24(3):156-160.

A Case of Gastric Schwannoma

Abstract

Most submucosal tumors of the stomach are of mesenchymal origin. Gastric schwannoma, which is a subset of mesenchymal tumors, is a rare tumor taking origin from Schwann's cells. A 61-year-old woman whose endoscopy showed a well circumscribed submucosal mass measuring 2.5 cm on the midbody of the stomach. Endosonographically, the tumor was well circumscribed, low echoic submucosal mass with cystic lesion in the 4th layer of the gastric wall. The patient underwent wedge resection. Microscopically, the cells were made up of irregular fasciculating bundles of spindle cells featured with benign nuclear atypia and peripheral lymphoid cell cuffing, involving muscularis propria. Immunohistochemical staining showed positivity for S-100 protein and the neuron-specific enolase, but were negative to CD 34, desmin and smooth muscle actin. From these findings, this tumor was diagnosed as a schwannoma.


MeSH Terms

Actins
Desmin
Endoscopy
Female
Humans
Lymphocytes
Middle Aged
Muscle, Smooth
Neurilemmoma*
Phosphopyruvate Hydratase
S100 Proteins
Stomach
Actins
Desmin
Phosphopyruvate Hydratase
S100 Proteins
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