Korean J Obstet Gynecol.  2006 May;49(5):1051-1059.

Perinatal Outcomes of Triplet Pregnancies

Affiliations
  • 1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. jsparkmd@snu.ac.kr

Abstract


OBJECTIVE
To evaluate the perinatal outcomes and maternal complications associated with triplet pregnancies.
METHODS
Medical records of consecutive triplet pregnancies delivered in ( )( )Hospital from 1997 to 2005 were reviewed for maternal and neonatal outcomes. Pregnancies associated with lethal congenital anomalies or the case that being delivered before 20 weeks of gestation were excluded. Neonatal outcomes included respiratory distress syndrome, retinopathy of prematurity, necrotizing enterocolitis, intraventricular hemorrhage and low Apgar scores, congenital anomaly and so on. Maternal outcomes included preeclampsia, preterm delivery, anemia and blood transfusion and so on.
RESULTS
The mean gestational age at delivery was 31.5+/-4.1 weeks, and the mean birth weight for triplets was 1,654.4+/-578.1 g. 31 of total 39 neonates (79.5%) were admitted to the neonatal intensive care unit, and 9 neonates (23.1%) received mechanical ventilator care as well. Neonatal death occurred in 6 of 39 neonates (15.4%). Congenital anomaly was seen in 3 of 39 neonates (7.7%). Hyperbilirubinemia developed in 16 of 39 neonates (44.4%). Respiratory distress syndrome developed in 3 of 39 neonates (7.7%). The most common maternal complication was preterm labor (76.9%), followed by anemia (46.1%), preterm premature rupture of membrane (30.8%) and blood transfusion (7.7%). Five patients (5/13, 38.5%) received tocolytic therapy.
CONCLUSION
The main cause of neonatal death in triplet pregnancies is the respiratory distress syndrome in extreme preterm delivery. The most common neonatal morbidities are hyperbilirubinemia and apnea of prematurity. There is no difference in neonatal outcomes according to birth order. The most common maternal complications are preterm delivery and anemia. The adverse outcomes of triplet pregnancies are mainly due to preterm delivery.

Keyword

Triplet pregnancy; Preterm delivery; Respiratory distress syndrome; Perinatal outcome

MeSH Terms

Anemia
Apnea
Birth Order
Birth Weight
Blood Transfusion
Enterocolitis, Necrotizing
Female
Gestational Age
Hemorrhage
Humans
Hyperbilirubinemia
Infant, Newborn
Intensive Care, Neonatal
Medical Records
Membranes
Obstetric Labor, Premature
Pre-Eclampsia
Pregnancy
Pregnancy, Triplet*
Retinopathy of Prematurity
Rupture
Tocolysis
Triplets*
Ventilators, Mechanical
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