Korean J Occup Environ Med.
2011 Sep;23(3):253-260.
Effects of Volatile Organic Compounds, and Formaldehyde on Heart Rate Variability among Elderly People in Seoul
- Affiliations
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- 1Department of Preventive Medicine, Seoul National University College of Medicine, Korea. ychong1@snu.ac.kr
- 2Department of Biostatistics and Epidemiology, Graduate School of Public Health, Seoul National University, Korea.
- 3Institute of Environmental Medicine, Seoul National University Medical Research Center, Korea.
- 4Department of Environmental Health, College of Health Sciences, Korea University, Korea.
Abstract
OBJECTIVES
The purpose of the present study was to investigate the effects of volatile organic compounds, and formaldehyde on heart rate variability among elderly people who are vulnerable to ambient pollution.
METHODS
From May to August of 2009, 57 subjects older than 60 years were recruited in this study. Indoor air pollutants (volatile organic compounds and formaldehyde) were measured by a personal passive sampler. Heart rate variability (HRV) was measured in the sitting position for five minutes and assessed by time-domain and frequency-domain.
RESULTS
Multiple linear regression analysis showed significantly less low-frequency (LF) and high-frequency (HF) associated with elevated benzene levels. Exposure to toluene was associated with decreases in the Standard deviation of the NN intervals (SDNN) and LF. SDNN and LF were negatively associated with the increment of ethylbenzene levels.
CONCLUSIONS
An adverse effect on cardiovascular function caused by volatile organic compounds was observed among the elderly people of Seoul even though indoor air pollutant levels were lower than the yearly average guideline for indoor air quality in Korea.
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