J Korean Breast Cancer Soc.  2000 Dec;3(2):171-180. 10.4048/jkbcs.2000.3.2.171.

Outcome of Surgical Excision for Isolated Locoregional Recurrence of Breast Cancer

Affiliations
  • 1Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.
  • 2Department of Radiation Oncology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.

Abstract

PURPOSE: Locoregional recurrence of breast cancer after surgery has been regarded as a harbinger of distant metastases. The present study was undertaken to determine survival following surgical excision of isolated locoregional recurrence and to analyze prognostic factors for impact on survival after locoregional recurrence. Also, this study may provide information on the benefit group from surgical management.
METHODS
From March 1993 to December 1998, of 43 patients with isolated locoregional recurrence after breast cancer surgery, 26 patients were treated with surgical excision with or without irradiation. Survival was analyzed according to prognostic factors retrospectively.
RESULTS
The median follow-up was 15 months. the 3-year disease-free and overall survival was 50% and 63% for locoregional recurrences treated with surgical resection, and 6% and 14% for patients without surgery, respectively(p=0.04, p=0.07). Univariative analysis demonstrated that the initial axillary node status and the disease-free interval were found to be significant prognostic factors for overall survival(p=0.04, p=0.06). The disease-free interval from surgery to recurrence was also a significant prognostic factor for disease-free survival(p=0.03).
CONCLUSION
These results suggest that isolated locoregional recurrence of breast cancer with a long disease-free interval and an initial node negative status may survived for long periods of time with aggressive surgical treatment.

Keyword

Breast cancer; Locoregional recurrence; Surgical treatment; Survival rate; Prognostic factors

MeSH Terms

Breast Neoplasms*
Breast*
Follow-Up Studies
Humans
Neoplasm Metastasis
Recurrence*
Retrospective Studies
Survival Rate

Cited by  1 articles

Surgical Treatment of Locoregional Recurrence in Breast Cancer
Jeoung Kyeung Kim, Byung Ho Son, Beom Seok Kwak, Ui Kang Hwang, Hee Jeong Kim, Jung Sun Lee, Soo Jung Hong, Min Sung Jung, Seung Do Ahn, Sei Hyun Ahn
J Breast Cancer. 2006;9(3):241-248.    doi: 10.4048/jbc.2006.9.3.241.

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