J Korean Acad Rehabil Med.
2008 Feb;32(1):116-118.
A Case of Fluoxetine Induced Mania in Poststroke Depression Patient: A case report
- Affiliations
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- 1Department of Rehabilitation Medicine, The Catholic University of Korea College of Medicine, Korea. drlee71@catholic.ac.kr
- 2Department of Pychiatry, The Catholic University of Korea College of Medicine, Korea.
Abstract
- Poststroke depression is very common and has been reported in as many as 40~50% of poststroke patients. The fluoxetine is one of the most frequently prescribed drugs for the treatment of poststroke depression. This serotonin selective reuptake inhibitor, known as generally safe and well tolerated drug, has been recently reported to induce mania. We report a case of fluoxetine-induced mania. A 64 year-old male, who has taken 10 mg of fluoxetine daily due to poststroke depression, presented elevated mood, hyperactivity, regressed behavior, excessive planning, sleep deterioration, and talkativeness abruptly. We were suspicious of fluoxetine- induced manic state and discontinued immediately fluoxetine without prescription of mood stabilizer. His symptoms had been ceased over two weeks.
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