J Clin Pathol Qual Control.  2001 Dec;23(2):319-323.

Current Status of the Quality Control of Blood Components at the Korean Red Cross Blood Centers

  • 1Blood Transfusion Research Institute, The Republic of Korea National Red Cross, Seoul, Korea. seo2023@netsgo.com


BACKGROUND: The quality of blood component is important for safe and effective transfusion therapy. Because almost all blood components used in hospitals are supplied by Red Cross Blood Centers, we investigated the current status of quality control of blood components produced by Korean Red Cross Blood Centers.
Quality control data of blood components from all blood centers were collected. The mean values and the testing frequencies of the volume, the count of erythrocytes, leukocytes and platelets, Hematocrit, pH, factor VIII activity, and microbial culture results were evaluated according to the blood components.
The testing frequency and the mean volume of tested bloods derived from 320 mL and 400 mL whole blood(WB) were 0.84%, 374 mL and 462 mL for WB; 0.86%, 196 mL and 248 mL for red blood cells(RBCs); 0.91%, 142 mL and 167 mL for fresh frozen plasma(FFP); 1.35%, 41 mL and 46 mL for platelet concentrates(PLT). Hematocrit of 320 mL and 400 mL WB were 36.7+/-1.2% and 40.7+/-1.0%. For each 320 mL and 400 mL derived blood, hematocrit of RBCs were 71.9+/-2.4 and 71.1+/-1.8%, erythrocytes count of RBCs were 1.61x10(12) and 1.78x10(12), platelet counts of PLT were 5.16x10(10) and 5.98x10(10). Factor Vlll activity of FFP was 100.7+/-12%, All bacterial cultures showed no growth for bacteria. The average pH of PLT was 7.1+/-0.1 and that of FFP was 6.9+/-0.1.
The mean volume of blood components and platelet count of PLT were adequate for quality but the testing frequencies were lower than those in developed country. The results of this study could be used as a basic data for developing the quality control standard of blood components production.

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