Clin Endosc.  2014 Nov;47(6):571-574. 10.5946/ce.2014.47.6.571.

Gastric Squamous Papilloma in a 52-Year-Old Female Patient

• Jang HH
• Kim HW
• Kim SJ
• Choi CW
• Park SB
• Song BJ
• Shin DH
• Kang DH

• KMID: 2134498
• DOI: http://doi.org/10.5946/ce.2014.47.6.571

Abstract

A papilloma is a benign epithelial lesion characterized by finger-like projections of tissue lined by an overgrowth of squamous cells and a core of connective tissue. We report a case of squamous papilloma on the cardia in a 52-year-old asymptomatic female. Endoscopy showed a 1-cm sized is polyp with hyperemic change originating from the cardia adjacent to the esophagogastric junction, the biopsy of which suggested a diagnosis of squamous papilloma. Endoscopic mucosal resection was performed to obtain a definite diagnosis and the polyp was completely removed. The histological result was compatible with squamous papilloma, and its surrounding tissues showed foveolar epithelium, which suggested a stomach origin. This is the first report of endoscopic resection of a gastric squamous papilloma. Squamous papilloma should be considered in the differential diagnosis of a gastric polyp, especially one in the cardia. As the prognostic value of a squamous papilloma is not well known, we recommend endoscopic resection to treat a gastric squamous papilloma, when possible.

Keyword

Papilloma; Stomach; Endoscopic resection; Polyps

MeSH Terms

Biopsy
Cardia
Connective Tissue
Diagnosis
Diagnosis, Differential
Endoscopy
Epithelium
Esophagogastric Junction
Female
Humans
Middle Aged*
Papilloma*
Polyps
Stomach

Figure

• 

  Fig. 1 Endoscopic findings. A 1-cm sized polyp is found at the cardia just below the esophagogastric junction. (A) Whitish granular surface in the front view. (B) Hyperemic surface in the retroflex view.

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  Fig. 2 Macroscopic findings of the resected specimen reveals a 1-cm sized polyp with a characteristic verrucous appearance.

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  Fig. 3 Microscopic findings. Histological findings of squamous papilloma showing. (A) Surrounding tissues containing foveolar epithelium, suggestive of stomach origin (H&E stain, ×20), and (B) proliferation of squamous epithelium without atypia, accompanied by a papillary projection with a fibrovascular core (H&E stain, ×200).

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  Fig. 4 Endoscopic findings show scar healing without local recurrence 6 months after resection.

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