Clin Endosc.  2014 Nov;47(6):490-496. 10.5946/ce.2014.47.6.490.

Screening for Gastric Cancer: The Usefulness of Endoscopy

Affiliations
  • 1Graduate School of Cancer Science and Policy, Goyang, Korea. kschoi@ncc.re.kr
  • 2National Cancer Control Institute, National Cancer Center, Goyang, Korea.

Abstract

Gastric cancer screening is common in countries with high prevalence rates of gastric cancer. However, data supporting the effectiveness of gastric cancer screening are lacking. Thus, the aim of this review was to examine the current evidence on gastric cancer screening. Herein, we reviewed radiographic and endoscopic tests as methods of gastric cancer screening. Previous cohort studies and case-control studies have demonstrated reduced gastric cancer mortality in study populations that had undergone gastric cancer screening with radiographic tests. Recently, a case-control study in Japan reported a 30% reduction in gastric cancer mortality when screening was undertaken via endoscopy. Also, endoscopic screening for gastric cancer exhibited higher sensitivity and specificity than radiographic screening. Moreover, most cost-effectiveness analyses on the best strategy for detecting early gastric cancer have generally concluded that endoscopy is more cost-effective than radiographic testing. Although data on the impact of endoscopy screening programs on gastric cancer mortality are limited, recent study results suggest that gastric cancer screening by endoscopy in average-risk populations performs better than radiography screening. Further evaluation of the impact of these screening methods should take into account cost and any associated reduction in gastric cancer mortality.

Keyword

Stomach neoplasms; Screening; Endoscopy; Upper gastrointestinal series

MeSH Terms

Case-Control Studies
Cohort Studies
Endoscopy*
Japan
Mass Screening*
Mortality
Prevalence
Radiography
Sensitivity and Specificity
Stomach Neoplasms*

Figure

  • Fig. 1 Trends in the use of upper gastrointestinal (UGI) series and endoscopy among participants in the National Cancer Screening Program in Korea from 2002 to 2011.


Cited by  3 articles

Factors Affecting Endoscopic Curative Resection of Gastric Cancer in the Population-Based Screening Era
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Clin Endosc. 2018;51(5):478-484.    doi: 10.5946/ce.2018.006.

Feedback Survey of the Effect, Burden, and Cost of the National Endoscopic Quality Assessment Program during the Past 5 Years in Korea
Yu Kyung Cho, Jeong Seop Moon, Dong Su Han, Yong Chan Lee, Yeol Kim, Bo Young Park, Il-Kwun Chung, Jin-Oh Kim, Jong Pil Im, Jae Myung Cha, Hyun Gun Kim, Sang Kil Lee, Hang Lak Lee, Jae Young Jang, Eun Sun Kim, Yunho Jung, Chang Mo Moon
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Trends in the Performance of the Korean National Cancer Screening Program for Gastric Cancer from 2007 to 2016
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Cancer Res Treat. 2022;54(3):842-849.    doi: 10.4143/crt.2021.482.


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