Brain Tumor Res Treat.  2014 Oct;2(2):76-80. 10.14791/btrt.2014.2.2.76.

Intradural Clival Chordoma: A Case Report

Affiliations
  • 1Department of Neurosurgery, Catholic University of Daegu College of Medicine, Daegu, Korea. gneuros@cu.ac.kr

Abstract

Clival chordoma is a rare intracranial neoplasm located in the clivus with bony extension and destruction. It is difficult to resect completely and generally has a poor prognosis. However, intradural clival chordomas have been reported with good surgical outcomes. We present a rare case of intradural chordoma and a review of the literature.

Keyword

Chordoma; Clivus; Intradural

MeSH Terms

Brain Neoplasms
Chordoma*
Cranial Fossa, Posterior
Prognosis

Figure

  • Fig. 1 Computed tomographic scan showing a normal appearance of clivus and intact cortical lining of posterior clival surface.

  • Fig. 2 Retroclival and prepontine mass with severe compression of pons in T2-weighted image (A) and T1-weighted image (B), with gadolinium enhancement (C).

  • Fig. 3 Gadolinium enhancement of sagittal image (A), cystic lesion in pons on T2-weighted image (B).

  • Fig. 4 Intraoperative photographs: exposed mass between 5th and 7, 8th cranial nerves (A), intact retroclival dura after resection of mass (B).

  • Fig. 5 Typical physaliphorous cells forming cord or nest within myxoid background (H&E, ×40) (A) and nuclear atypia (black arrows) (×400) (B), negative immunohistochemical staining for Ki 67 antigen (×200) (C), positive immunohistochemical staining for keratin AE1/AE3 (×40) (D).


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