Ann Clin Microbiol.  2015 Dec;18(4):111-118. 10.5145/ACM.2015.18.4.111.

Comparison of Antibiotic Resistance Rate of Medically Important Microorganisms between Japan and Korea

• Shibayama
• Lee H
• Kim S

• KMID: 2133607
• DOI: http://doi.org/10.5145/ACM.2015.18.4.111

Abstract

BACKGROUND
A surveillance system for antibiotic resistance is well organized in both Japan and Korea; however, a comparative analysis by microorganism has not previously been conducted.
METHODS
We compared the latest antibiotic resistance rates of medically important pathogens, such as Staphylococcus aureus, enterococci, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii, between Japan and Korea. Data were collected by JANIS (Japan Nosocomial Infections Surveillance) and KARMS (Korean Antimicrobial Resistance Monitoring System) from 2007-2012.
RESULTS
In 2012, the proportions of oxacillin-resistant S. aureus, vancomycin-resistant Enterococcus faecium (VRE), cefotaxime-resistant E. coli, ceftazidime-resistant K. pneumoniae, imipenem-resistant P. aeruginosa, and imipenem-resistant A. baumannii were 53%, 0.4%, 16.6%, 2.9%, 18.5%, and 2% in Japan and 67%, 32%, 29%, 40%, 28%, and 70% in Korea, respectively.
CONCLUSION
There were large differences in the frequencies of VRE, ceftazidime-resistant K. pneumoniae, and imipenem-resistant A. baumannii between Japan and Korea. A collaborative study to probe the differences in the antibiotic resistance rates between the two countries should be performed.

Keyword

Acinetobacter baumannii; Carbapenem; Resistance; Methicillin-resistant Staphylococcus aureus; Vancomycin-resistant enterococci

MeSH Terms

Acinetobacter baumannii
Cross Infection
Drug Resistance, Microbial*
Enterococcus faecium
Escherichia coli
Japan*
Klebsiella pneumoniae
Korea*
Methicillin-Resistant Staphylococcus aureus
Pneumonia
Pseudomonas aeruginosa
Staphylococcus aureus

Figure

• 

  Fig. 1. (A) Oxacillin resistance rate of Staphylococcus aureus. (B) Vancomycin resistance rate of Enterococcus faecium.

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