Nucl Med Mol Imaging.  2015 Dec;49(4):321-324. 10.1007/s13139-015-0353-1.

Multicentric Primary Angiosarcoma of Bone Mimicking Metastasis on 18F-FDG PET/CT in a Patient with a History of Sigmoid Colon Cancer: a Case Report

• Yoo MY
• Lee ES
• Kim SK
• Park SY
• Kwon Y
• Yun T
• Kim TS

• KMID: 2132239
• DOI: http://doi.org/10.1007/s13139-015-0353-1

Abstract

Primary angiosarcoma of the bone (PAB) is a rare and fatal high-grade malignant vascular bone tumor. We report a rare case of multicentric PAB mimicking bone metastasis in a 59-year-old female patient with a history of sigmoid colon cancer. This patient complained of lower back and pelvic pain and presented with multiple osteolytic bone lesions on plain radiography and pelvic computed tomography. First, bone metastasis of sigmoid colon cancer was suspected. However, on the 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan, the patient presented unusual multiple hypermetabolic osteolytic bone lesions involving contiguous bones of the lower half of the body. After bone biopsy, these lesions were confirmed to be multicentric PAB. To the best of our knowledge, this is the first case report of an 18F-FDG PET/CT scan in a patient with multicentric primary bone angiosarcoma.

Keyword

Primary angiosarcoma; Bone; 18F-FDG; positron-emission tomography

MeSH Terms

Biopsy
Colon, Sigmoid*
Electrons
Female
Fluorodeoxyglucose F18*
Hemangiosarcoma*
Humans
Middle Aged
Neoplasm Metastasis*
Pelvic Pain
Positron-Emission Tomography
Positron-Emission Tomography and Computed Tomography*
Radiography
Sigmoid Neoplasms*
Fluorodeoxyglucose F18