J Rhinol.  2012 Nov;19(2):127-130.

Very Late Recurrent Maxillary Sinus Squamous Cell Carcinoma on the Skin Graft Site 16 years after the Treatment

• Seong SY
• Hyun DW
• Yoon JH
• Kim CH

Abstract

Maxillary sinus cancer is anatomically located adjacent to the orbit and the skull base. Local recurrence is by far the most common cause of treatment failure and the long-term survival rates is low. Local recurrence is usually happened within 2 years after initial treatment. Late recurrence is generally defined as a recurrence 5 years after initial treatment. But, late recurrence cases of maxillary sinus cancer is very rare, especially 10 years after treatment. We report a case of late recurrence on the previous skin graft site 16 years after the treatment of maxillary sinus squamous cell carcinoma in a 66-yr-old man. The patient was treated with surgical wide excision and skin graft. No recurrence was developed after one and a half year and we discussed the pathogenesis of this very late recurrent case.

Keyword

Late recurrence; Maxillary sinus cancer; Clonal extension

MeSH Terms

Carcinoma, Squamous Cell
Humans
Maxillary Sinus
Maxillary Sinus Neoplasms
Orbit
Recurrence
Skin
Skull Base
Survival Rate
Transplants
Treatment Failure