J Rhinol.  1998 May;5(1):72-75.

Two Cases of Malignant Fibrous Histiocytoma in the Nasal Cavity and Paranasal Sinus

  • 1Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Inha University, Incheon, Korea.
  • 2Department of Pathology, College of Medicine, Inha University, Incheon, Korea.


Malignant fibrous histiocytoma (MFH) is a recently documented variety of soft-tissue sarcoma that occurs infrequently in the head and neck region. Typically, it demonstrates fibrogenic differentiation, most commonly in a storiform pattern. Because MFH is highly recurrent and has a high metastatic rate, which is attributable to the microscopic spread of the lesion from the main body of the tumor, the neoplasm necessitates wide surgical resection. The authors recently experienced two cases of MFH developed in the nasal cavity and paranasal sinus. The first case (in a 60-year-old man), treated by total maxillectomy, is now in its third year of follow-up without recurrence and metastatic lesion. The second case (in a 49-year-old man), incidentally detected following endoscopic sinus surgery for sinusitis, was treated by medial maxillectomy. He died due to local recurrence and distant pulmonary metastasis one and half months after the operation.


Malignant fibrous histiocytoma; Nasal cavity; Paranasal sinus
Full Text Links
  • JR
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr