J Rhinol.  1997 May;4(1):57-60.

Primitive Neuroectodermal Tumor of Nasal Cavity: Case Report

  • 1Department of Otorhinolaryngology- Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
  • 2Department of Surgical Pathology, Korea University College of Medicine, Seoul, Korea.


The primitive neuroectodermal tumor is a highly malignant small round cell tumor characterized by neuroectodermal origin and poor prognosis. The thoracopulmonary region is known to be the most common site of the disease, with peak incidence during adolescence. Primitive neuroectodermal tumors are very rarely reported in the head and neck area, and there have been only a few involving the nasal cavity. We treated a 60 year-old female patient who had nasal obstruction over a three-month period with radical surgery and postoperative radiation therapy. This paper presents our diagnostic workup and approach in treating this unique tumor, and the immunohistochemical findings. A guideline for the treatment of this aggressive neoplasm is reviewed with our experiences in treating this primitive neuroectodermal tumor of the nasal cavity by combined treatment modalities.


Primitive neuroectodermal tumor; Nasal cavity
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