Korean J Otorhinolaryngol-Head Neck Surg.  2015 Nov;58(11):759-763. 10.3342/kjorl-hns.2015.58.11.759.

The Effect of Physical Characteristics on Sleep Disturbance and Cardiovascular Complications in Obstructive Sleep Apnea Patients: The Preliminary Study

Affiliations
  • 1Department of Psychiatry, Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
  • 2Department of Otorhinolaryngology, School of Medicine, Catholic University of Daegu, Daegu, Korea. hsseung@cu.ac.kr
  • 3Department of Otolaryngology, Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
  • 4Department of Neurology, Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
  • 5Department of Neurology, School of Medicine, Catholic University of Daegu, Daegu, Korea.

Abstract

BACKGROUND AND OBJECTIVES
Obstructive sleep apnea (OSA) is a common yet an under-diagnosed sleep related breathing disorder associated with many adverse health outcomes. OSA is commonly associated with cardiovascular disorders that include coronary artery disease, heart failure, hypertension, cardiac arrhythmias and stroke. The aim of this study was to investigate the physical characteristics of OSA patients as a screening test for sleep apnea associated cardiovascular disease.
SUBJECTS AND METHOD
One hundred twenty-six adult OSA patients were enrolled in this study. All subjects underwent an overnight polysomnography (PSG) and were determined body mass index (BMI), neck circumstance, waist circumstance, tonsil size, etc. Cardiovascular events, such as hypertension, cardiovascular accident, myocardial infarction, and angina were analyzed. The correlation and multiple regression analysis were conducted to find influential and predictive factors of cardiovascular complications of OSA.
RESULTS
PSG findings, apnea-hypopnea index (AHI), minimal oxygen saturation, and oxygen desaturation index were associated with BMI, neck circumstance, and waist circumstance. Tonsil size was also associated with AHI and oxygen desaturation index. However, PSG results were not associated with cardiovascular accidents of OSA patients. Hypertension was associated with tonsil size, angina was associated with Mallampati score and cardiovascular accident was associated with tonsil size.
CONCLUSION
Although we cannot find the statistical relation between PSG results and cardiovascular disease, tonsil size and Mallampati score influenced the risk of cardiovascular accident.

Keyword

Angina; Cardiovascular accident; Hypertension; Obstructive sleep apnea; Polysomnography

MeSH Terms

Adult
Arrhythmias, Cardiac
Body Mass Index
Cardiovascular Diseases
Coronary Artery Disease
Heart Failure
Humans
Hypertension
Mass Screening
Myocardial Infarction
Neck
Oxygen
Palatine Tonsil
Polysomnography
Respiration
Sleep Apnea Syndromes
Sleep Apnea, Obstructive*
Stroke
Oxygen
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