Korean J Vet Res.  2015 Mar;55(1):53-56. 10.14405/kjvr.2015.55.1.53.

Genetic analysis of env and gag gene fragments of bovine leukemia virus identified in cattle from Korea

Affiliations
  • 1Division of Animal Diseases Diagnosis, Animal and Plant Quarantine Agency, Anyang 430-757, Korea. naturelkk@korea.kr
  • 2College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 151-742, Korea. parksec@snu.ac.kr

Abstract

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis. This study was conducted to clarify the molecular characteristics of BLVs obtained from a specific region in Korea. Proviral BLVs were detected in anti-BLV antibody-positive blood samples by PCR. Env and gag fragments were sequenced and compared to previously published reference sequences. Analysis of the env gene sequence revealed that the YI strain was highly similar to genotype 1, including United States and Japanese strains. The gag gene sequence had the highest degree of similarity with a Japanese strain.

Keyword

bovine leukemia virus; cattle; env gene; gag gene

MeSH Terms

Animals
Asian Continental Ancestry Group
Cattle*
Enzootic Bovine Leukosis
Genes, env
Genes, gag*
Genotype
Humans
Korea
Leukemia Virus, Bovine*
Polymerase Chain Reaction
United States
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